Target Name: SLC6A12
NCBI ID: G6539
Review Report on SLC6A12 Target / Biomarker Content of Review Report on SLC6A12 Target / Biomarker
SLC6A12
Other Name(s): Solute carrier family 6 member 12 | S6A12_HUMAN | OTTHUMP00000115358 | Na(+)/Cl(-) betaine/GABA transporter | Sodium- and chloride-dependent betaine transporter | SLC6A12 variant 1 | Na+- and Cl- dependent betaine transporter | FLJ38727 | Betain-GABA transporter | solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 | solute carrier family 6 (neurotransmitter transporter), member 12 | BGT-1 | BGT1 | betaine/GABA transporter-1 | gamma-aminobutyric acid transporter | solute carrier family 6 member 12 | Solute carrier family 6 member 12, transcript variant 1 | Solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 | Gamma-aminobutyric acid transporter | Betaine gamma-amino-n-butyric acid transporter | GAT2

SLC6A12: A Protein Involved in Neurotransmitter and Ion Transport

SLC6A12 is a protein that is expressed in various tissues throughout the body. It is a member of the Solute Carrier Family 6, which is a large family of transmembrane proteins that play an important role in the transport of various molecules across cell membranes. SLC6A12 is primarily expressed in the brain, where it is involved in the transport of glutamate, a highly important neurotransmitter that is involved in many different brain functions.

SLC6A12 is a protein that is known for its unique structure and biology. It is a member of the SLC6A family, which consists of a variety of related proteins that share a conserved transmembrane domain and a unique type of nucleotide transport mechanism. This family of proteins is characterized by its ability to transport a wide variety of molecules across cell membranes, including ions, nutrients, and toxins.

One of the unique features of SLC6A12 is its expression pattern. It is primarily expressed in the brain, where it is found in the postsynaptic layer of neurons. This layer is responsible for transmitting signals from the brain to other parts of the body, and as such, it is a critical site for the expression of many different proteins that are involved in neural communication. The expression of SLC6A12 in the postsynaptic layer of neurons suggests that it may be a drug target or biomarker that can be used to diagnose or treat a variety of neurological disorders.

SLC6A12 is also involved in the transport of other molecules across cell membranes, including ions such as calcium and magnesium. These ions are involved in many different cellular processes, including muscle contractions, nerve impulse transmission, and cell signaling. Therefore, studying the function of SLC6A12 in ion transport can provide an in-depth understanding of the functions and mechanisms of the nervous system and provide new ideas for the treatment of neurodegenerative diseases.

In addition, SLC6A12 is also known for its role in the transport of neurotransmitters, such as dopamine and GABA. These molecules are involved in the transmission of signals within the brain, and as such, their expression and function are closely associated with the proper functioning of the brain. The identification and manipulation of SLC6A12 as a drug target or biomarker for neurotransmitter transport may provide new insights into the treatment of psychiatric and neurological disorders.

In addition to its role in neurotransmitter transport, SLC6A12 is also involved in the regulation of many different cellular processes. For example, it has been shown to be involved in the regulation of cell adhesion, a process that is critical for the development and maintenance of tissues and organs. It is also involved in the regulation of ion channels, which are responsible for the flow of ions through cell membranes. These channels are critical for the proper functioning of many different cellular processes, including muscle contractions and nerve impulse transmission. Therefore, studying the function of SLC6A12 in ion channel regulation can provide an in-depth understanding of cell physiological functions and provide new ideas for the treatment of diseases caused by ion disorders.

In addition, SLC6A12 is also known for its role in the regulation of gene expression. It is a powerful transcription factor that can bind to specific DNA sequences and regulate the expression of genes that are involved in many different cellular processes. This regulation of gene expression is critical for the development and maintenance of tissues and organs, and as such, its dysfunction may be involved in the development of many different diseases. The identification and manipulation of SLC6A12 as a drug target or biomarker for gene regulation may provide new insights into the treatment of a variety of diseases.

In conclusion, SLC6A12 is a protein that is expressed in various tissues throughout the body and is involved in the transport of various molecules across cell membranes, including neurotransmitters and ions. Its unique structure and biology, as well as its role in the regulation of many different cellular processes, make it an attractive

Protein Name: Solute Carrier Family 6 Member 12

Functions: Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation

The "SLC6A12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC6A12 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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