Target Name: SLC8A2
NCBI ID: G6543
Review Report on SLC8A2 Target / Biomarker Content of Review Report on SLC8A2 Target / Biomarker
SLC8A2
Other Name(s): Sodium/calcium exchanger 2 | KIAA1087 | Na+/Ca2+-exchanging protein Nac2 | NCX2 | Na+/Ca2+-exchanging protein 2 | solute carrier family 8 member 2 | Solute carrier family 8 member 2 | Solute carrier family 8 member A2 | DKFZp761D171 | Na(+)/Ca(2+)-exchange protein 2 | solute carrier family 8 member A2 | solute carrier family 8 (sodium/calcium exchanger), member 2 | NAC2_HUMAN

SLC8A2: A Promising Drug Target and Biomarker for the Treatment of the corresponding Disease

Abstract:

Sodium/calcium exchanger 2 (SLC8A2) is a protein that plays a crucial role in the regulation of essential nutrients, including sodium and calcium homeostasis. SLC8A2 has been identified as a potential drug target and biomarker for the treatment of various diseases, including hypertension, heart failure, and cancer. This article will provide an overview of SLC8A2, its function in the body, potential drug targets, and its potential as a biomarker for disease diagnosis and monitoring.

Introduction:

Sodium/calcium exchanger 2 (SLC8A2) is a protein that is expressed in various tissues throughout the body and is involved in the regulation of essential nutrients, including sodium and calcium homeostasis. SLC8A2 is a member of the SLC family of proteins, which are involved in the transport of various anions and cations across cell membranes. SLC8A2 is primarily localized to the endoplasmic reticulum (ER) and has been shown to play a role in the regulation of sodium and calcium homeostasis, as well as the transport of other molecules across cell membranes.

Function:

SLC8A2 is involved in the regulation of sodium and calcium homeostasis by facilitating the exchange of sodium and calcium ions across the cell membrane. SLC8A2 helps to maintain the proper levels of sodium and calcium in the body by regulating the amount of these ions that enter or exit cells. This is critical for maintaining the proper function of various tissues and organs, including muscle, nerve, and heart cells. In addition, SLC8A2 is also involved in the regulation of other ions, including potassium and magnesium, which are also essential nutrients that play important roles in various physiological processes.

Potential Drug Targets:

SLC8A2 has been identified as a potential drug target for the treatment of various diseases due to its involvement in the regulation of essential nutrients. One of the main targets for SLC8A2 is the regulation of sodium and calcium homeostasis, which is critical for maintaining the proper function of various and tissues.

Hypertension is a common disease that is characterized by an increase in blood pressure. SLC8A2 has been shown to play a role in the regulation of sodium and calcium homeostasis, which is critical for maintaining the proper function of blood vessels. Therefore, SLC8A2 may be a potential drug target for the treatment of hypertension.

Heart failure is a condition that is characterized by the inability of the heart to pump enough blood to meet the body's needs. SLC8A2 has been shown to play a role in the regulation of sodium and calcium homeostasis, which is critical for maintaining the proper function of heart cells. Therefore, SLC8A2 may be a potential drug target for the treatment of heart failure.

Cancer is a disease that can affect any part of the body and is characterized by the formation of tumors. SLC8A2 has been shown to play a role in the regulation of sodium and calcium homeostasis, which is critical for maintaining the proper function of cancer cells. Therefore, SLC8A2 may be a potential drug target for the treatment of cancer.

Potential Biomarkers:

SLC8A2 has also been identified as a potential biomarker for the diagnosis and monitoring of various diseases. SLC8A2 has been shown to play a role in the regulation of sodium and calcium homeostasis, which is critical for the function of many physiological processes in the body. Therefore , SLC8A2 may be a potential biomarker for the diagnosis and monitoring of various diseases, including hypertension, heart failure, and cancer.

Conclusion:

Sodium/calcium exchanger 2 (SLC8A2) is a protein that plays a crucial role in the regulation of essential nutrients, including sodium and calcium homeostasis. SLC8A2 has

Protein Name: Solute Carrier Family 8 Member A2

Functions: Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca(2+) and Na(+) excretion

The "SLC8A2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC8A2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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