Target Name: TAPBP
NCBI ID: G6892
Review Report on TAPBP Target / Biomarker Content of Review Report on TAPBP Target / Biomarker
TAPBP
Other Name(s): TAP-binding protein | NGS17 | TAP binding protein | TAP binding protein, transcript variant 3 | NGS-17 | TAP-associated protein | TAP binding protein (tapasin) | TPSN | TAPA | TAP binding protein, transcript variant 1 | Tapasin | Tapasin (isoform 3) | Tapasin (isoform 1) | TPN | TPSN_HUMAN | TAPBP variant 3 | TAPBP variant 1

TAPBP: A Protein Involved in Cell Signaling and Adhesion

TAPBP (TAP-binding protein) is a protein that is expressed in various tissues and cells in the human body. It is a member of the tyrosine phosphatase family and is involved in the regulation of cellular signaling pathways. TAPBP has been shown to play a role in a variety of physiological processes, including cell signaling, cell adhesion, and inflammation. As a result, TAPBP has potential as a drug target or biomarker.

The tyrosine phosphatase family is a group of enzymes that play a critical role in the regulation of cellular signaling pathways. These enzymes catalyze the transfer of a phosphate group from a tyrosine molecule to another molecule, resulting in the formation of a covalent complex. This process is highly regulated by the protein TAP (Tyrosine-protein kinase) and the protein tyrosine phosphatase (TAPBP).

TAPBP is a 24-kDa protein that is expressed in various tissues and cells in the human body. It is a member of the tyrosine phosphatase family and is involved in the regulation of cellular signaling pathways. TAPBP has been shown to play a role in a variety of physiological processes, including cell signaling, cell adhesion, and inflammation.

One of the key functions of TAPBP is its role in cell signaling. TAPBP is involved in the regulation of the signals that are transduced by intracellular signaling molecules, such as tyrosine. This involves the formation of a covalent complex between TAPBP and a tyrosine molecule, resulting in the formation of a protein tyrosine. This process is critical for the regulation of cellular signaling pathways, including cell growth, differentiation, and inflammation.

Another function of TAPBP is its role in cell adhesion. TAPBP is involved in the regulation of cell-cell adhesion, which is critical for the development and maintenance of tissues and organs. This involves the formation of a tight junctions between cells, which allows them to exchange nutrients and other substances.

In addition to its role in cell signaling and cell adhesion, TAPBP is also involved in the regulation of inflammation. TAPBP has been shown to play a role in the regulation of the immune response, including the regulation of T cells and the formation of immune complexes.

Given its involvement in a variety of physiological processes, TAPBP has potential as a drug target or biomarker. For example, TAPBP has been shown to be a promising target for small molecule inhibitors, with several studies reporting that these inhibitors can inhibit the activity of TAPBP and its downstream targets. In addition, TAPBP has been shown to be involved in the regulation of cellular signaling pathways, which makes it a potential target for drugs that target these pathways.

Overall, TAPBP is a protein that is involved in the regulation of cellular signaling pathways and has potential as a drug target or biomarker. Further research is needed to fully understand the role of TAPBP in these processes and to develop effective treatments based on these insights.

Protein Name: TAP Binding Protein

Functions: Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading)

The "TAPBP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TAPBP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TAPBPL | TAPT1 | TAPT1-AS1 | TARBP1 | TARBP2 | TARDBP | TARDBPP1 | TARDBPP3 | TARID | TARM1 | TARP | TARS1 | TARS2 | TARS3 | TAS1R1 | TAS1R2 | TAS1R3 | TAS2R1 | TAS2R10 | TAS2R13 | TAS2R14 | TAS2R16 | TAS2R19 | TAS2R20 | TAS2R3 | TAS2R30 | TAS2R31 | TAS2R38 | TAS2R39 | TAS2R4 | TAS2R40 | TAS2R41 | TAS2R42 | TAS2R43 | TAS2R45 | TAS2R46 | TAS2R5 | TAS2R50 | TAS2R60 | TAS2R63P | TAS2R64P | TAS2R7 | TAS2R8 | TAS2R9 | TASL | TASOR | TASOR2 | TASP1 | Taste receptor type 2 | Taste Receptors Type 1 | TAT | TAT-AS1 | TATDN1 | TATDN2 | TATDN2P3 | TATDN3 | TAX1BP1 | TAX1BP3 | TBATA | TBC1D1 | TBC1D10A | TBC1D10B | TBC1D10C | TBC1D12 | TBC1D13 | TBC1D14 | TBC1D15 | TBC1D16 | TBC1D17 | TBC1D19 | TBC1D2 | TBC1D20 | TBC1D21 | TBC1D22A | TBC1D22A-AS1 | TBC1D22B | TBC1D23 | TBC1D24 | TBC1D25 | TBC1D26 | TBC1D27P | TBC1D28 | TBC1D29P | TBC1D2B | TBC1D3 | TBC1D30 | TBC1D31 | TBC1D32 | TBC1D3B | TBC1D3C | TBC1D3F | TBC1D3G | TBC1D3H | TBC1D3L | TBC1D3P1 | TBC1D3P2 | TBC1D4 | TBC1D5 | TBC1D7 | TBC1D8