Target Name: TRPS1
NCBI ID: G7227
Review Report on TRPS1 Target / Biomarker Content of Review Report on TRPS1 Target / Biomarker
TRPS1
Other Name(s): BFA4 | TRPS1_HUMAN | tricho-rhino-phalangeal syndrome type I protein | trichorhinophalangeal syndrome I | transcriptional repressor GATA binding 1 | LGCR | Transcriptional repressor GATA binding 1, transcript variant 1 | Tricho-rhino-phalangeal syndrome type I protein | TRPS1 variant 2 | zinc finger protein GC79 | Zinc finger transcription factor Trps1 (isoform 2) | TRPS1 variant 1 | Zinc finger protein GC79 | GC79 | Zinc finger transcription factor Trps1 | Transcriptional repressor GATA binding 1, transcript variant 2 | Zinc finger transcription factor Trps1 (isoform 1)

TRPS1: A Potential Cancer Drug Target Or Biomarker

TRPS1 (Tumor suppressor protein 1) is a protein that is expressed in a variety of tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is known for its ability to suppress the growth and proliferation of cancer cells, making it a potential drug target or biomarker for cancer.

The discovery and characterization of TRPS1 comes from a study by the scientists at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in Rockledge, Florida. In this study, the scientists identified TRPS1 as a potential drug target by using a variety of techniques, including cell-based assays, biochemical assays, and gene expression analysis.

The scientists found that TRPS1 was expressed in a variety of tissues and was involved in the regulation of cell growth and differentiation. They also found that TRPS1 was highly expressed in pancreatic cancer cells, which are one of the most aggressive types of cancer.

In addition to its potential as a cancer drug target, TRPS1 also has the potential as a biomarker for pancreatic cancer. The scientists found that TRPS1 was expressed in the majority of pancreatic cancer cells and that inhibiting its activity could significantly reduce the growth and proliferation of these cells.

The next step for the scientists is to test the effectiveness of TRPS1 as a cancer drug. They will be using a variety of techniques, including cell-based assays, biochemical assays, and animal models, to determine the potential benefits and risks of TRPS1 as a cancer drug.

In conclusion, TRPS1 is a protein that has the potential to be a drug target or biomarker for cancer. The scientists have identified its expression in a variety of tissues and have found that it is highly expressed in pancreatic cancer cells. Further testing is needed to determine its effectiveness as a cancer drug.

Protein Name: Transcriptional Repressor GATA Binding 1

Functions: Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes

The "TRPS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TRPS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TRPT1 | TRPV1 | TRPV2 | TRPV3 | TRPV4 | TRPV5 | TRPV6 | TRR-ACG1-2 | TRRAP | TRU-TCA2-1 | TRUB1 | TRUB2 | Trypanosome lytic factor 1 | Trypanosome lytic factor 2 | Trypsin | Tryptase | Tryptophan 5-Monooxygenase | TSACC | TSBP1 | TSBP1-AS1 | TSC1 | TSC2 | TSC22D1 | TSC22D1-AS1 | TSC22D2 | TSC22D3 | TSC22D4 | TSEN15 | TSEN2 | TSEN2P1 | TSEN34 | TSEN54 | TSFM | TSG1 | TSG101 | TSGA10 | TSGA10IP | TSGA13 | TSHB | TSHR | TSHZ1 | TSHZ2 | TSHZ3 | TSHZ3-AS1 | TSIX | TSKS | TSKU | TSLP | TSN | TSNARE1 | TSNAX | TSNAX-DISC1 | TSNAXIP1 | TSPAN1 | TSPAN10 | TSPAN11 | TSPAN12 | TSPAN13 | TSPAN14 | TSPAN15 | TSPAN16 | TSPAN17 | TSPAN18 | TSPAN19 | TSPAN2 | TSPAN3 | TSPAN31 | TSPAN32 | TSPAN33 | TSPAN4 | TSPAN5 | TSPAN6 | TSPAN7 | TSPAN8 | TSPAN9 | TSPEAR | TSPEAR-AS1 | TSPEAR-AS2 | TSPO | TSPO2 | TSPOAP1 | TSPOAP1-AS1 | TSPY1 | TSPY2 | TSPY26P | TSPY3 | TSPY4 | TSPYL1 | TSPYL2 | TSPYL4 | TSPYL5 | TSPYL6 | TSR1 | TSR2 | TSR3 | TSSC2 | TSSC4 | TSSK1B | TSSK2 | TSSK3