Target Name: AKAP14
NCBI ID: G158798
Review Report on AKAP14 Target / Biomarker Content of Review Report on AKAP14 Target / Biomarker
AKAP14
Other Name(s): A-kinase anchoring protein 14, transcript variant 1 | protein kinase A-anchoring protein 14 | A-kinase anchor protein 28 kDa | AKAP28 | AKAP-14 | AKAP14 variant 1 | AKAP 28 | A-kinase anchor protein 14 (isoform a) | Protein kinase A-anchoring protein 14 | AKA28_HUMAN | A kinase (PRKA) anchor protein 14 | A-kinase anchor protein 14 | PRKA14 | A-kinase anchoring protein 14 | A-kinase anchoring protein 28

AKAP14: A Protein Involved in Many Cellular Processes and Diseases

AKAP14 is a protein that is expressed in various tissues throughout the body, including the brain, heart, kidneys, and liver. It is a member of the A-kinase anchoring protein (AAP) family, which is a subfamily of the protein kinase superfamily. This protein is known to play a role in the regulation of cellular processes that are important for many different cellular functions, including cell signaling, cell adhesion, and cell survival.

The AKAP14 gene has four splice variants, which result in the production of four different isoforms of the protein. These isoforms are produced by alternative splicing of the gene, and they have different effects on the structure and function of the protein. The most abundant isoform is a protein that has 115 amino acid residues, while the other isoforms have between 98 and 121 amino acid residues.

The protein encoded by the AKAP14 gene is involved in many different cellular processes. For example, it has been shown to play a role in the regulation of cell signaling pathways that are important for many different cellular functions, including cell proliferation, differentiation, and survival. It is also involved in the regulation of cell adhesion, and has been shown to interact with various signaling proteins that are involved in these processes.

In addition to its role in cellular signaling, AKAP14 has also been shown to play a role in the regulation of cellular processes that are important for many different cellular functions, including cell survival. For example, studies have shown that the protein can promote the survival of cancer cells, and that it may be a potential drug target for this disease.

The AKAP14 gene has also been implicated in a number of different diseases and disorders. For example, it has been shown to be involved in the development and progression of various types of cancer, including breast cancer, lung cancer, and colorectal cancer. It is also involved in the regulation of many different signaling pathways, and has been implicated in a number of different diseases and disorders, including neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Despite these promising findings, much more research is needed to fully understand the role of AKAP14 in cellular processes and the development of diseases. The protein is currently being studied in a number of research contexts, including in the development of new treatments for cancer and other diseases.

In conclusion, AKAP14 is a protein that is involved in many different cellular processes and has been implicated in a number of different diseases and disorders. While more research is needed to fully understand its role, it is a promising target for new drug development and research.

Protein Name: A-kinase Anchoring Protein 14

Functions: Binds to type II regulatory subunits of protein kinase A and anchors/targets them

The "AKAP14 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AKAP14 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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