AK2: A Protein Involved in Multiple Signaling Pathways and Potential Drug Target Or Biomarker

Target Name: AK2

NCBI ID: G204

Content of Review Report on AK2 Target / Biomarker

AK2

AK2: A Protein Involved in Multiple Signaling Pathways and Potential Drug Target Or Biomarker

AK2 (Alkylator 2) is a protein that is expressed in various tissues throughout the body, including the brain, heart, kidneys, and gastrointestinal tract. It is a key regulator of cellular signaling pathways, and its levels have been linked to a number of diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. In recent years, researchers have been interested in exploring the potential of AK2 as a drug target or biomarker, and a number of studies have suggested that it may be a promising candidate for both.

The protein encoded by the AK2 gene is a 24-kDa glycoprotein that is expressed in a variety of tissues throughout the body. It is highly conserved across species, and has been shown to be involved in a number of cellular signaling pathways, including the regulation of cell adhesion, migration, and survival. In addition, AK2 has been shown to play a role in the regulation of inflammation and immune responses.

One of the key functions of AK2 is its role as a negative regulator of the TGF-β pathway, which is involved in the regulation of cell growth, differentiation, and survival. The TGF-β pathway is a well-established cancer-promoting pathway that is involved in the development of many types of cancer, including breast, lung, and colorectal cancer. In recent years, researchers have been interested in exploring the potential of inhibiting the TGF-β pathway as a means of treating cancer. AK2 has been shown to be a potential target for this purpose, as it has been shown to inhibit the activity of the TGF-β receptor in a variety of cell types.

In addition to its role in the TGF-β pathway, AK2 has also been shown to be involved in the regulation of a number of other signaling pathways, including the regulation of cell adhesion, migration, and survival. For example, AK2 has been shown to play a role in the regulation of tight junction formation, which is important for the proper functioning of tissues such as blood vessels and epithelial cells. In addition, AK2 has been shown to play a role in the regulation of cell survival, as well as the regulation of cell proliferation.

The levels of AK2 have been linked to a number of diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. For example, studies have shown that high levels of AK2 are associated with an increased risk of developing cancer, and that inhibiting the activity of AK2 may be a promising approach for the treatment of cancer. In addition, AK2 has been shown to be involved in the regulation of a number of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. In these conditions, the levels of AK2 are often increased, and inhibiting the activity of AK2 may be a potential approach for the treatment of these disorders.

In addition to its potential as a drug target or biomarker, AK2 has also been shown to be a potential biomarker for a number of diseases. For example, studies have shown that the levels of AK2 are often increased in a variety of diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. In these conditions, the levels of AK2 may be used as a biomarker to track the progression of the disease and the effectiveness of treatments.

In conclusion, AK2 is a protein that has been shown to be involved in a number of cellular signaling pathways, including the regulation of cell adhesion, migration, and survival. In recent years, researchers have been interested in exploring the potential of AK2 as a drug target or biomarker, and a number of studies have suggested that it may be a promising candidate for both. Further research is needed to fully understand the role of AK2 in these processes, and to determine its potential as a drug

Protein Name: Adenylate Kinase 2

Functions: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis

The "AK2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AK2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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