Target Name: AKAP12
NCBI ID: G9590
Review Report on AKAP12 Target / Biomarker Content of Review Report on AKAP12 Target / Biomarker
AKAP12
Other Name(s): A-kinase anchor protein 250 kDa | A-kinase anchoring protein 12, transcript variant 1 | AKAP12 variant 1 | AKAP250 | Myasthenia gravis autoantigen | AKAP-12 | A-kinase anchor protein 12 (isoform 1) | DKFZp686M0430 | A kinase (PRKA) anchor protein 12 | AKAP 250 | Gravin | DKFZp686O0331 | A-kinase anchor protein 12 | SSeCKS | A-kinase anchor protein, 250kDa | myasthenia gravis autoantigen gravin | kinase scaffold protein gravin | A-kinase anchor protein 12 (isoform 2) | Myasthenia gravis autoantigen gravin | Src-Suppressed C Kinase Substrate | Kinase scaffold protein gravin | A-kinase anchoring protein 12 | A-kinase anchoring protein 12, transcript variant 2 | AKAP12 variant 2 | AKA12_HUMAN

AKAP12: A Potential Drug Target and Biomarker forAKAP12 (A-kinase Anchor Protein 250 kDa)

AKAP12 (A-kinase anchor protein 250 kDa) is a protein that is expressed in various tissues and cell types in the human body. It plays a crucial role in the regulation of cell signaling pathways, including the cAMP/cGMP signaling pathway. This protein has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

During the past decade, significant research has been conducted to understand the role of AKAP12 in various biological processes. Several studies have shown that AKAP12 plays a critical role in the regulation of cell signaling pathways, including the regulation of cell proliferation, apoptosis, and inflammation.

In addition to its role in cellular signaling pathways, AKAP12 has also been shown to play a potential role in disease diagnosis and treatment. Several studies have shown that high levels of AKAP12 expression are associated with various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. Additionally, studies have also shown that inhibiting the activity of AKAP12 has the potential to be a therapeutic approach for these diseases.

Targeting AKAP12 as a Drug Interceptor

The A-kinase anchor protein 250 kDa (AKAP12) is a protein that can be targeted as a drug interceptor. Drugs that inhibit the activity of AKAP12 have been shown to have therapeutic potential for various diseases.

One of the main mechanisms by which drugs can inhibit the activity of AKAP12 is by blocking the formation of the A-kinase complex. The A-kinase complex is a protein that consists of the A-kinase subunit and several regulatory proteins that help to regulate the activity of the A-kinase enzyme.

Inhibitors of AKAP12 have been shown to be effective in treating various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. For example, studies have shown that inhibitors of AKAP12 have the potential to be effective in treating breast cancer by inhibiting the formation of the A-kinase complex.

Another mechanism by which drugs can inhibit the activity of AKAP12 is by blocking the function of the A-kinase enzyme itself. The A-kinase enzyme is responsible for the phosphorylation of various targets, including the protein p120GTP. Inhibitors of the A-kinase enzyme have been shown to have therapeutic potential in treating various diseases, including neurodegenerative diseases.

In conclusion, inhibitors of AKAP12 have the potential to be effective in treating various diseases by blocking the activity of the A-kinase enzyme or the formation of the A-kinase complex.

Biomarker for Disease Diagnosis and Treatment

AKAP12 has also been shown to play a critical role in disease diagnosis and treatment. High levels of AKAP12 expression are associated with various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. Additionally, studies have shown that inhibiting the activity of AKAP12 has the potential to be a therapeutic approach for these diseases.

One of the main applications of AKAP12 as a biomarker is its potential to be used as a diagnostic marker for various diseases. Studies have shown that high levels of AKAP12 expression are associated with the development of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

In addition to its potential as a diagnostic marker, AKAP12 has also been shown to play a critical role in disease treatment. Studies have shown that inhibiting the activity of AKAP12 has the potential to be a therapeutic approach for various diseases, including cancer, neurodegenerative diseases, and

Protein Name: A-kinase Anchoring Protein 12

Functions: Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC)

The "AKAP12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AKAP12 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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