EIF3FP3: A Protein Regulating Translation Initiation in Eukaryotic Cells

Target Name: EIF3FP3

NCBI ID: G339799

EIF3FP3

Other Name(s): Eukaryotic translation initiation factor 3, subunit F pseudogene 3 | eukaryotic translation initiation factor 3 subunit F pseudogene 3

EIF3FP3: A Protein Regulating Translation Initiation in Eukaryotic Cells

EIF3FP3, also known as EUKaryotic Translation Initiation Factor 3 subunit F pseudogene 3, is a protein that plays a crucial role in the process of translation initiation in eukaryotic cells. It is a key regulator of the 40S ribosome, which is responsible for translating mRNAs into functional proteins. EIF3FP3 is a pseudogene, which means that it is a non-coding gene that has some degree of functional redundancy or evolutionary conservation.

The 40S ribosome is a complex protein that consists of multiple subunits that work together to initiate the translation of mRNAs. EIF3FP3 is one of the key subunits of the 40S ribosome and plays a critical role in this process. It is involved in the recruitment of mRNAs to the ribosome, as well as in the formation of the ribosome-mRNA interaction complex.

EIF3FP3 is a 21-kDa protein that contains 115 amino acid residues. It belongs to the Hsp70 protein family, which is a family of cytoplasmic proteins that play a variety of roles in various cellular processes. EIF3FP3 is primarily expressed in the cytoplasm of eukaryotic cells and is also found in the nucleus.

The function of EIF3FP3 is highly conserved across various species, which suggests that it is an ancient gene that has been preserved over evolutionary time. It is highly expressed in many different organisms, including bacteria, yeast, and plants. EIF3FP3 has also been shown to be involved in various cellular processes, including cell growth, cell division, and stress response.

Due to its role in the 40S ribosome, EIF3FP3 is of particular interest as a potential drug target or biomarker. If an inhibitor of EIF3FP3 were to be developed and used in therapeutic treatments, it could potentially interfere with the translation of mRNAs, leading to various cellular consequences. For example, if an inhibitor were to be used to prevent the formation of the ribosome-mRNA interaction complex, it could lead to decreased protein synthesis and growth.

In addition to its potential therapeutic applications, EIF3FP3 is also of interest as a potential biomarker. The translation of mRNAs into functional proteins is a critical process that is closely monitored by various cellular signaling pathways. EIF3FP3 is involved in this process, and its expression levels can be affected by various cellular factors, including stress, growth conditions, and mutations. Therefore, changes in EIF3FP3 expression levels could be an indicator of cellular stress or dysfunction.

In conclusion, EIF3FP3 is a protein that plays a critical role in the process of translation initiation in eukaryotic cells. Its function is highly conserved across various species and is associated with various cellular processes, including cell growth, cell division, and stress response. As a potential drug target or biomarker, EIF3FP3 is of particular interest due to its potential therapeutic applications and its involvement in the translation of mRNAs into functional proteins. Further research is needed to fully understand the role of EIF3FP3 in cellular processes and its potential as a drug target or biomarker.

Protein Name: Eukaryotic Translation Initiation Factor 3 Subunit F Pseudogene 3

The "EIF3FP3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EIF3FP3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets