PAQR8: Potential Drug Target and Biomarker (G85315)

Target Name: PAQR8

NCBI ID: G85315

PAQR8

PAQR8: Potential Drug Target and Biomarker

Progesterone and adipoQ receptor family member 8 (PAQR8) is a protein that is expressed in various tissues throughout the body. It is a member of the PAQR family, which includes proteins that are involved in the regulation of glucose and lipid metabolism. The PAQR8 protein is known for its role in the regulation of lipid metabolism, and it is potential drug target or biomarker in various diseases.

PAQR8 function

PAQR8 is a protein that is expressed in various tissues throughout the body, including the liver, muscle, and heart. It is a member of the PAQR family, which includes proteins that are involved in the regulation of glucose and lipid metabolism. The PAQR8 protein is known for its role in the regulation of lipid metabolism, and it is potential drug target or biomarker in various diseases.

PAQR8 is involved in the regulation of lipid metabolism by activating the PPAR未 gene. PPAR未 is a gene that encodes a protein that is involved in the regulation of lipid metabolism. When PAQR8 is activated, it helps to activate the PPAR未 gene, which leads to the production of PPAR未 protein. PPAR未 protein is involved in the regulation of lipid metabolism by activating genes that are involved in the production of fatty acids and lipids.

PAQR8 is also involved in the regulation of glucose metabolism by activating the GLUT1 gene. GLUT1 is a gene that encodes a protein that is involved in the regulation of glucose metabolism. When PAQR8 is activated, it helps to activate the GLUT1 gene, which leads to the production of GLUT1 protein. GLUT1 protein is involved in the regulation of glucose metabolism by activating genes that are involved in the production of glucose.

PAQR8 is a potential drug target

PAQR8 is a potential drug target because of its role in the regulation of lipid metabolism and glucose metabolism. Drugs that are designed to target PAQR8 have been shown to be effective in treating various diseases, including obesity, diabetes, and cardiovascular disease. For example, a drug called obeticholic acid (OBT) has been shown to be effective in treating obesity by inhibiting the activity of PAQR8.

PAQR8 is also a potential biomarker for certain diseases. For example, people with type 2 diabetes may have increased levels of PAQR8 in their blood. This suggests that PAQR8 may be a useful biomarker for the diagnosis and treatment of type 2 diabetes. Additionally, people with obesity may have lower levels of PAQR8 in their blood, which could be used as a biomarker for the diagnosis and treatment of obesity.

Conclusion

PAQR8 is a protein that is involved in the regulation of lipid metabolism and glucose metabolism. It is a member of the PAQR family and is known for its role in the regulation of these processes. PAQR8 is potential drug target or biomarker in various diseases, including obesity, diabetes, and cardiovascular disease. Further research is needed to fully understand the function and potential of PAQR8.

Protein Name: Progestin And AdipoQ Receptor Family Member 8

Functions: Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (By similarity). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870)

The "PAQR8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PAQR8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets