Target Name: MCM3AP
NCBI ID: G8888
Review Report on MCM3AP Target / Biomarker Content of Review Report on MCM3AP Target / Biomarker
MCM3AP
Other Name(s): germinal-centre associated nuclear protein | MCM3 acetylating protein | GANP protein | KIAA0572 | GANP | MCM3 import protein | PNRIID | SAC3 | MCM3 acetyltransferase | 80 kDa MCM3-associated protein | Minichromosome maintenance deficient (S. cerevisiae) 3-associated protein | Minichromosome maintenance complex component 3 associated protein | Germinal-center associated nuclear protein | MCM3 minichromosome maintenance deficient 3 associated protein | germinal center-associated nuclear protein | minichromosome maintenance complex component 3 associated protein | GANP_HUMAN | MAP80 | Germinal center-associated nuclear protein | Minichromosome maintenance protein 3 associated protein

MCM3AP: A Potential Drug Target and Biomarker

MCM3AP, a nuclear protein located in the germinal center, is a key regulator of the immune response and inflammation. It has been identified as a potential drug target and biomarker for several diseases, including multiple sclerosis, rheumatoid arthritis, and cancer.

The immune system is a critical component of the body's defense against infection and disease. The germinal center is a central part of the immune system that plays a crucial role in the generation of new immune cells. MCM3AP is a key regulator of the germinal center and has been shown to participate in the regulation of T cell development and function.

MCM3AP has been shown to play a role in the regulation of T cell development and function. MCM3AP has been shown to interact with the transcription factor PDGF-1, which is critical for T cell development. MCM3AP has also been shown to play a role in the regulation of T cell receptor (TCR) gene expression.

MCM3AP has also been shown to be involved in the regulation of inflammation. MCM3AP has been shown to interact with the transcription factor NF-kappa-B, which is involved in the regulation of inflammation. MCM3AP has also been shown to play a role in the regulation of cytokine production, which is a critical component of the immune response.

In addition to its role in the immune system, MCM3AP has also been shown to play a role in the regulation of cell survival. MCM3AP has been shown to interact with the transcription factor p53, which is involved in the regulation of DNA damage repair. MCM3AP has also been shown to play a role in the regulation of cell apoptosis, which is a natural process that helps to remove damaged or dysfunctional cells from the body.

MCM3AP has been shown to be involved in the regulation of multiple diseases, including multiple sclerosis, rheumatoid arthritis, and cancer. MCM3AP has been shown to play a role in the regulation of the development and progression of multiple sclerosis, a disease characterized by the destruction of the central nervous system. MCM3AP has also been shown to play a role in the regulation of the development and progression of rheumatoid arthritis, a disease characterized by inflammation and joint damage. MCM3AP has also been shown to play a role in the regulation of the development and progression of cancer, a disease characterized by the formation of tumors.

In conclusion, MCM3AP is a key regulator of the immune system and has been shown to play a role in the regulation of T cell development and function, inflammation, and cell survival. As a potential drug target and biomarker, MCM3AP is a promising target for the development of new treatments for multiple sclerosis, rheumatoid arthritis, and cancer. Further research is needed to fully understand the role of MCM3AP in the immune system and its potential as a drug target.

Protein Name: Minichromosome Maintenance Complex Component 3 Associated Protein

Functions: As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (PubMed:20005110, PubMed:20384790, PubMed:23591820, PubMed:22307388). Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations (PubMed:23652018)

The "MCM3AP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MCM3AP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MCM3AP-AS1 | MCM4 | MCM5 | MCM6 | MCM7 | MCM8 | MCM8-MCM9 complex | MCM9 | MCMBP | MCMDC2 | MCOLN1 | MCOLN2 | MCOLN3 | MCPH1 | MCPH1-AS1 | MCPH1-DT | MCRIP1 | MCRIP2 | MCRS1 | MCTP1 | MCTP2 | MCTS1 | MCTS2 | MCU | MCUB | MCUR1 | MDC1 | MDFI | MDFIC | MDGA1 | MDGA2 | MDH1 | MDH1B | MDH2 | MDK | MDM1 | MDM2 | MDM4 | MDN1 | MDS2 | ME1 | ME2 | ME3 | MEA1 | MEAF6 | MEAF6P1 | MEAK7 | Mechanoelectrical transducer (MET) channel | Mechanosensitive Ion Channel | MECOM | MECOM-AS1 | MeCP1 histone deacetylase (HDAC) complex | MECP2 | MECR | MED1 | MED10 | MED11 | MED12 | MED12L | MED13 | MED13L | MED14 | MED14P1 | MED15 | MED15P8 | MED16 | MED17 | MED18 | MED19 | MED20 | MED21 | MED22 | MED23 | MED24 | MED25 | MED26 | MED27 | MED28 | MED29 | MED30 | MED31 | MED4 | MED4-AS1 | MED6 | MED7 | MED8 | MED9 | MEDAG | Mediator Complex | Mediator of RNA Polymerase II Transcription | MEF2A | MEF2B | MEF2C | MEF2C-AS1 | MEF2C-AS2 | MEF2D | MEFV | MEG3 | MEG8 | MEG9