ZFAND2A: A Potential Drug Target and Biomarker for Neurodegenerative Disorders

Target Name: ZFAND2A

NCBI ID: G90637

ZFAND2A

ZFAND2A: A Potential Drug Target and Biomarker for Neurodegenerative Disorders

Abstract:

Zinc finger AN1-type containing 2A (ZFAND2A) is a gene that has been identified as a potential drug target and biomarker for neurodegenerative disorders. ZFAND2A is a protein that contains a zinc finger domain and a unique N-terminal extension that is composed of 24 amino acids. The zinc finger domain is known for its ability to interact with various molecules, including transcription factors, leading to the potential for ZFAND2A to play a role in gene regulation.

Several studies have suggested that ZFAND2A may be involved in the development and progression of neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. These studies have identified ZFAND2A as a potential drug target by virtue of its involvement in the regulation of gene expression and its expression in the brains of individuals with neurodegenerative disorders.

In addition to its potential as a drug target, ZFAND2A has also been identified as a potential biomarker for neurodegenerative disorders. The ability of ZFAND2A to be expressed and processed in the brains of individuals with neurodegenerative disorders has led to the potential for its use as a diagnostic or predictive marker for these disorders.

The Protein Structure and Functions

ZFAND2A is a protein that contains a single open reading frame (ORF) and a protein body with several conserved domains, including a zinc finger domain, a N-terminal extension, and a unique C-terminus. The zinc finger domain is the most well-studied, as it is known to play a role in the regulation of gene expression.

The zinc finger domain is a structural element that consists of four amino acids: Zn-F-Y-E-Q. Zn is a highly reactive metal that is involved in a wide range of cellular processes, including DNA replication, gene expression, and signaling. The F-Y-E-Q motif in the zinc finger domain is responsible for the interaction of Zn with various molecules, including transcription factors.

The N-terminal extension of ZFAND2A consists of 24 amino acids that are unique to this gene. The extension is thought to be involved in the regulation of protein expression and has been implicated in the development and progression of neurodegenerative disorders.

The Unique C-terminus of ZFAND2A

The unique C-terminus of ZFAND2A has also been studied extensively. The C-terminus is a 24 amino acid region that is unique to this gene and is located at the end of the protein. The C-terminus has been shown to be involved in the regulation of protein stability and has been implicated in the development and progression of neurodegenerative disorders.

Potential Therapeutic Interventions

Several studies have suggested that ZFAND2A may be a potential drug target for neurodegenerative disorders. The zinc finger domain and the N-terminal extension of ZFAND2A have been shown to be involved in the regulation of gene expression, making them potential targets for small molecules or antibodies that can modulate gene expression.

In addition to its potential as a drug target, ZFAND2A has also been identified as a potential biomarker for neurodegenerative disorders. The ability of ZFAND2A to be expressed and processed in the brains of individuals with neurodegenerative disorders has led to the potential for its use as a diagnostic or predictive marker for these disorders.

Conclusion

Zinc finger AN1-type containing 2A (ZFAND2A) is a gene that has been identified as a potential drug target and biomarker for neurodegenerative disorders. The zinc finger domain and the N-terminal extension of ZFAND2A have been shown to be involved in the regulation of gene expression and have been implicated in the development and progression of

Protein Name: Zinc Finger AN1-type Containing 2A

The "ZFAND2A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZFAND2A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets