SLC16A5: A Protein Involved in Various Physiological Processes and Potential Drug Targets

Target Name: SLC16A5

NCBI ID: G9121

SLC16A5

SLC16A5: A Protein Involved in Various Physiological Processes and Potential Drug Targets

SLC16A5 (MCT 6) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the selective sodium channel subfamily 16 (SLC16) and is responsible for transmitting electrical signals through sodium channels in the plasma membrane of cells. MCT 6 is also known as NHE3 and has been shown to play a role in a variety of physiological processes, including muscle contractions and blood pressure regulation.

SLC16A5 has also been shown to be a potential drug target in several diseases, including heart disease, hypertension, and neurodegenerative disorders. Researchers have identified several potential drug compounds that can inhibit SLC16A5 and have shown that these compounds can improve the function of the nervous system in various models.

One of the most promising compounds that has been shown to interact with SLC16A5 is called NX-1455. This compound is a potassium channel inhibitor and has been shown to improve the function of the nervous system in animal models of neurodegenerative disorders. NX-1455 has also been shown to increase the amount of brain-derived neurotrophic factor (BDNF) in the brain, which is a protein that promotes the growth and survival of nerve cells.

Another compound that has been shown to interact with SLC16A5 is called LY-2118. This compound is a sodium channel inhibitor and has been shown to improve the function of the nervous system in animal models of hypertension. LY-2118 has also been shown to increase the amount of brain-derived neurotrophic factor (BDNF) in the brain, which is a protein that promotes the growth and survival of nerve cells.

Research has also shown that SLC16A5 is involved in the regulation of muscle contractions. When muscle contractions are needed, SLC16A5 helps to regulate the flow of calcium ions into the muscle cells, which is necessary for muscle relaxation and the initiation of muscle contractions.

In addition to its role in muscle contractions, SLC16A5 is also involved in the regulation of blood pressure. SLC16A5 has been shown to help to relax the smooth muscle in the walls of blood vessels, which can help to reduce the pressure on the blood vessels. This is important for maintaining proper blood pressure and for the overall health of the cardiovascular system.

Overall, SLC16A5 is a protein that plays a critical role in various physiological processes in the body. It is a potential drug target for several diseases, including heart disease, hypertension, and neurodegenerative disorders. The studies on SLC16A5 have shown that it is involved in the regulation of sodium channels and muscle contractions, and that it is important for the proper function of the nervous system. Further research is needed to fully understand the role of SLC16A5 in the regulation of physiological processes and to develop effective treatments for the diseases that are associated with its dysfunction.

Protein Name: Solute Carrier Family 16 Member 5

Functions: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity)

The "SLC16A5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC16A5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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