UTP14C: A Potential Drug Target (G9724)

Target Name: UTP14C

NCBI ID: G9724

UTP14C

UTP14C: A Potential Drug Target

UTP14C (2700066J21Rik), a protein encoded in the UTP gene, is a potential drug target (or biomarker) that has been identified for its role in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its function and unique features make it an attractive target for drug development, as it has been shown to play a crucial role in the development and progression of these diseases.

The UTP gene is a member of the superfamily of UTP-containing proteins, which are characterized by a conserved domain that includes a single transmembrane region and a nucleotide-binding oligomerization domain (N-O domain). UTP14C is a 21 kDa protein that contains a unique N-O domain, which is composed of a variable region and a constant region. The variable region includes a 65 amino acid residue that is involved in protein-protein interactions and functions as a critical signaling module.

UTP14C is involved in various cellular processes, including DNA replication, transcription, and gene regulation. Its role in these processes has been confirmed by various biochemical and cellular studies. For example, UTP14C has been shown to play a critical role in the regulation of DNA replication in eukaryotic cells. It has been shown to interact with the enzyme responsible for DNA replication, leading to the formation of a complex that is involved in the initiation of DNA replication.

In addition to its role in DNA replication, UTP14C is also involved in the regulation of gene expression. Its N-O domain has been shown to interact with various transcription factors, including the RNA polymerase II (RNA-P2) complex. This interaction allows UTP14C to regulate the activity of RNA-P2 and influence the expression of target genes.

The unique features of UTP14C make it an attractive drug target. Its N-O domain is involved in multiple cellular processes, making it a potential target for small molecules that can modulate its activity. Additionally, its role in regulating DNA replication and gene expression makes it a potential target for drugs that are designed to prevent the development of cancer or neurodegenerative diseases.

In conclusion, UTP14C (2700066J21Rik) is a protein that has been identified as a potential drug target (or biomarker) due to its unique features and its involvement in various diseases. Its role in the regulation of DNA replication and gene expression makes it an attractive target for small molecules that can modulate its activity. Further research is needed to determine the full scope of UTP14C's potential as a drug target and to develop effective therapies that can target its activity.

Protein Name: UTP14C Small Subunit Processome Component

Functions: Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis (By similarity)

The "UTP14C Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UTP14C comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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