GNA15: Key Regulator of GPCR Signaling and Cellular Processes

Target Name: GNA15

NCBI ID: G2769

GNA15

GNA15: Key Regulator of GPCR Signaling and Cellular Processes

GNA15 (GNA15_HUMAN) is a gene that encodes for a protein known as GNA15. GNA15 is a key regulator of the intracellular signaling pathway known as the G-protein-coupled receptor (GPCR) signaling pathway. This pathway is involved in many important cellular processes, including sensory perception, neurotransmission, and hormone signaling.

GNA15 is a 21-kDa protein that is expressed in many different tissues and cells in the body. It is primarily localized to the endoplasmic reticulum (ER), a structure that is responsible for the final sorting of proteins into different intracellular compartments. GNA15 is known to play a role in the trafficking of other proteins to their final destinations, including the transport of neurotransmitters such as dopamine, serotonin, and GABA.

GNA15 is also involved in the regulation of gene expression. It has been shown to play a role in the negative regulation of gene expression in many different cell types, including neurons and cancer cells. This is accomplished through the interaction of GNA15 with specific DNA-binding proteins, known as transcription factors.

One of the unique features of GNA15 is its ability to interact with multiple transcription factors. This allows GNA15 to play a role in the regulation of a wide range of gene expression, including the expression of many different neurotransmitter genes.

GNA15 is also known to be involved in the regulation of cellular signaling pathways that are involved in pain perception and neurotransmission. For example, GNA15 has been shown to play a role in the regulation of pain signaling, as well as the regulation of neurotransmission in the brain.

GNA15 is also a potential drug target in the future. Its involvement in the regulation of many different cellular processes makes it an attractive target for small molecule inhibitors. Additionally, its involvement in the regulation of gene expression makes it a potential biomarker for a variety of diseases, including neurodegenerative disorders and psychiatric illnesses.

In conclusion, GNA15 is a protein that plays a critical role in the regulation of many different cellular processes in the body. Its involvement in the GPCR signaling pathway, as well as its involvement in the regulation of gene expression and cellular signaling pathways, makes it an attractive target for small molecule inhibitors. Further research is needed to fully understand the role of GNA15 in cellular processes and its potential as a drug target.

Protein Name: G Protein Subunit Alpha 15

Functions: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems

The "GNA15 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GNA15 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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