GMNC: A Potential Drug Target for Neurological Disorders (G647309)

Target Name: GMNC

NCBI ID: G647309

GMNC

Other Name(s): GEMC1_HUMAN | Geminin coiled-coil domain containing | geminin coiled-coil domain containing | GEMC1 | Geminin coiled-coil domain-containing protein 1

GMNC: A Potential Drug Target for Neurological Disorders

Gene Methylation Technology is an effective method for detecting gene expression and gene regulation. By analyzing the epigenetic regulation of gene expression, we can reveal the importance and mechanism of genes in areas such as nervous system development, disease treatment, and drug development. In recent years, with the development of gene methylation technology, researchers have paid more and more attention to the role of gene methylation in the regulation of drug targets. This article will focus on GMNC (GEMC1_HUMAN), a potential drug target.

Basic information about GMNC:
GMNC is a transcription factor mainly expressed on neurons. Its encoding gene is HUMAN Glypican-3 (HGK3). HGK3 is a neurotrophic factor that plays an important role in neuronal growth and development. GMNC plays an important role in neuronal synapse formation, cell cycle regulation, and neuronal apoptosis.

Pharmacological significance of GMNC:
GMNC has high prospects in drug research and development, and as a potential drug target, it is of great significance in the treatment of various neurological diseases. Currently, researchers are exploring the role of GMNC in treating neurological diseases such as Alzheimer's disease, Parkinson's disease, and epilepsy.

Biological functions of GMNC:
The main mechanism by which GMNC exerts biological functions in neurons is to control neuronal growth and development by regulating gene expression. Specifically, GMNC controls gene activity by binding to DNA, thereby affecting gene expression in neurons. In addition, GMNC can also affect neuronal apoptosis and play a key role in neuronal damage and disease.

Clinical application prospects of GMNC:
With the deepening of research, GMNC, as a drug target, has broad application prospects in the treatment of neurological diseases. For example, by inhibiting the activity of GMNC, neuronal apoptosis can be slowed down, thereby improving recovery after neuronal injury. In addition, GMNC can also regulate the growth and development of neurons, thus having a potential role in the treatment of various neurological diseases.

in conclusion:
GMNC is a transcription factor that plays an important role in the nervous system. By studying the biological functions and pharmacological significance of GMNC, its potential and mechanism of action in the treatment of neurological diseases can be revealed. With the deepening of research, GMNC will become an important drug target and provide new ideas and methods for the treatment of various neurological diseases.

Protein Name: Geminin Coiled-coil Domain Containing

Functions: Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2-dependent recruitment of CDC45L onto replication origins (By similarity)

The "GMNC Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GMNC comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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