Target Name: LACTB
NCBI ID: G114294
Review Report on LACTB Target / Biomarker Content of Review Report on LACTB Target / Biomarker
LACTB
Other Name(s): MRPL56 | FLJ14902 | Mitochondrial ribosomal protein L56 | Beta-lactamase-like protein LACTB | Serine beta-lactamase-like protein LACTB, mitochondrial (isoform a) | LACTB variant 1 | Serine beta-lactamase-like protein LACTB, mitochondrial (isoform b) | LACTB_HUMAN | mitochondrial 39S ribosomal protein L56 | G24 | Lactamase beta, transcript variant 1 | lactamase beta | Mitochondrial 39S ribosomal protein L56 | Lactamase beta, transcript variant 2 | Serine beta lactamase-like protein LACTB | serine beta-lactamase-like protein, mitochondrial | LACTB variant 2 | Serine beta-lactamase-like protein LACTB, mitochondrial

LACTB: A Protein Involved in Cell Signaling, Metabolism and Stress Response

LACTB (leucine-rich repeat-containing protein 56) is a protein that is expressed in various tissues throughout the body, including the brain, muscle, and heart. It is characterized by the presence of a unique repeat sequence, known as a leucine- rich repeat, which is found in the cytoplasm of the cells in which it is expressed.

Recent studies have suggested that LACTB may have important roles in several biological processes, including cell signaling, metabolism, and stress response. Based on these findings, LACTB has been identified as a potential drug target or biomarker for a variety of diseases.

One potential mechanism by which LACTB may be involved in disease is its role in cell signaling. LACTB is a protein that is involved in the regulation of several intracellular signaling pathways, including the TGF-β pathway and the Wnt/FGF pathway. These pathways are involved in a wide range of biological processes, including cell growth, differentiation, and survival.

In addition to its role in cell signaling, LACTB has also been shown to be involved in metabolism. LACTB has been shown to be involved in the metabolism of fats and carbohydrates, which are critical for maintaining energy homeostasis in the body.

Another potential mechanism by which LACTB may be involved in disease is its role in stress response. LACTB is known to be involved in the regulation of stress responses in cells, including the regulation of inflammation and the modulation of cellular communications.

Based on these findings, LACTB has been identified as a potential drug target or biomarker for a variety of diseases, including cancer, metabolism-related diseases, and neurodegenerative diseases.

In conclusion, LACTB is a protein that is expressed in various tissues throughout the body, and it has been shown to be involved in a wide range of biological processes. Its unique leucine-rich repeat and its involvement in cell signaling, metabolism, and stress response make it a promising target for future research and development of new therapeutics. Further studies are needed to fully understand the role of LACTB in disease and to determine its potential as a drug target or biomarker.

Protein Name: Lactamase Beta

Functions: Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism (PubMed:28329758). Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism (PubMed:28329758). It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein (PubMed:28329758). Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism (PubMed:28329758)

The "LACTB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LACTB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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LACTB2 | LACTB2-AS1 | LACTBL1 | LAD1 | LAG3 | LAGE3 | LAIR1 | LAIR2 | LALBA | LAMA1 | LAMA2 | LAMA3 | LAMA4 | LAMA5 | LAMB1 | LAMB2 | LAMB2P1 | LAMB3 | LAMB4 | LAMC1 | LAMC1-AS1 | LAMC2 | LAMC3 | Laminin-5 | Laminins | LAMP1 | LAMP2 | LAMP3 | LAMP5 | LAMP5-AS1 | LAMTOR1 | LAMTOR2 | LAMTOR3 | LAMTOR3P1 | LAMTOR4 | LAMTOR5 | LAMTOR5-AS1 | LanC-like proteins | LANCL1 | LANCL1-AS1 | LANCL2 | LANCL3 | LAP3 | LAP3P2 | LAPTM4A | LAPTM4B | LAPTM4BP2 | LAPTM5 | Large Conductance BK(Ca) Potassium Channel (Maxi K+ Channel) | LARGE-AS1 | LARGE1 | LARGE2 | LARP1 | LARP1B | LARP4 | LARP4B | LARP4P | LARP6 | LARP7 | LARS1 | LARS2 | LAS1L | LASP1 | LAT | LAT2 | LATS1 | LATS2 | LAX1 | LAYN | LBH | LBHD1 | LBP | LBR | LBX1 | LBX1-AS1 | LBX2 | LBX2-AS1 | LCA5 | LCA5L | LCAL1 | LCAT | LCDR | LCE1A | LCE1B | LCE1C | LCE1D | LCE1E | LCE1F | LCE2A | LCE2B | LCE2C | LCE2D | LCE3A | LCE3B | LCE3C | LCE3D | LCE3E | LCE4A | LCE5A | LCE6A