ZNF440: A Key Regulator of Neural Development (G126070)
ZNF440: A Key Regulator of Neural Development
ZNF440 (ZN440_HUMAN), a protein encoded by the ZNF4 gene, is a key regulator of neural development, and its dysfunction has been implicated in a number of neurological and psychiatric disorders. The ZNF4 gene is part of the ZNF41 complex, a group of genes that are involved in the development and maintenance of neural stem cells. ZNF440 is a 21-kDa protein that is expressed in a variety of tissues, including brain, heart, and muscle.
The ZNF4 gene is named after the ZNF41 complex because it is part of that complex, which consists of four genes: ZNF4, ZNF2, ZNF5, and ZNF6. The ZNF4 gene is responsible for the production of ZNF440, which is a key component of the ZNF41 complex.
ZNF440 plays a crucial role in the development and maintenance of neural stem cells. During development, neural stem cells are responsible for the formation of the nervous system and the development of various tissues. Stem cells are highly plastic and can differentiate into a wide variety of cell types, including neurons, glial cells, and other neural cell types. The ZNF440 protein is involved in the regulation of stem cell proliferation and differentiation, as well as the formation of neural tissues.
In addition to its role in neural development, ZNF440 has also been implicated in the regulation of stem cell self-renewal. Self-renewal is the ability of stem cells to maintain a constant number of cells throughout their lifespan, and it is a critical factor in the development and maintenance of tissues. The ZNF440 protein is involved in the regulation of stem cell self-renewal by promoting the expression of genes that are involved in cell cycle arrest and apoptosis.
The ZNF440 protein is also involved in the regulation of neural repair and regeneration. After injury or disease, neural cells are often damaged and cannot repair themselves effectively. The ZNF440 protein is involved in the regulation of neural repair and regeneration by promoting the expression of genes that promote the formation of new neurons and the growth of damaged neural tissues.
In addition to its role in neural development and repair, ZNF440 has also been implicated in the regulation of a variety of other processes. For example, the ZNF440 protein is involved in the regulation of cell adhesion, the formation of tight junctions, and the regulation of ion channels. It is also involved in the regulation of inflammation and immune response, and it is involved in the regulation of cell signaling pathways that are involved in pain perception and neurotransmission.
Due to its involvement in a wide range of cellular processes, the ZNF440 protein is a potential drug target or biomarker for a variety of neurological and psychiatric disorders. For example, the ZNF440 gene has been implicated in the development of several neurological disorders, including autism, schizophrenia, and Parkinson's disease. In addition, the ZNF440 protein has been shown to be involved in the regulation of pain perception and neurotransmission, which could make it a potential target for the treatment of chronic pain.
In conclusion, ZNF440 (ZN440_HUMAN) is a protein that is involved in a wide range of cellular processes that are important for neural development and maintenance. Its dysfunction has been implicated in the development of several neurological and psychiatric disorders, and its potential as a drug target or biomarker makes it an attractive target for future research. Further studies are needed to fully understand the role of ZNF440 in neural development and maintenance, as well as its potential as a drug target or biomarker.
Protein Name: Zinc Finger Protein 440
Functions: May be involved in transcriptional regulation
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More Common Targets
ZNF441 | ZNF442 | ZNF443 | ZNF444 | ZNF445 | ZNF446 | ZNF449 | ZNF45 | ZNF451 | ZNF454 | ZNF460 | ZNF461 | ZNF462 | ZNF467 | ZNF468 | ZNF469 | ZNF470 | ZNF471 | ZNF473 | ZNF473CR | ZNF479 | ZNF48 | ZNF480 | ZNF483 | ZNF484 | ZNF485 | ZNF486 | ZNF487 | ZNF488 | ZNF490 | ZNF491 | ZNF492 | ZNF493 | ZNF496 | ZNF497 | ZNF497-AS1 | ZNF500 | ZNF501 | ZNF502 | ZNF503 | ZNF503-AS1 | ZNF503-AS2 | ZNF506 | ZNF507 | ZNF510 | ZNF511 | ZNF512 | ZNF512B | ZNF513 | ZNF514 | ZNF516 | ZNF516-DT | ZNF517 | ZNF518A | ZNF518B | ZNF519 | ZNF519P3 | ZNF521 | ZNF524 | ZNF525 | ZNF526 | ZNF527 | ZNF528 | ZNF528-AS1 | ZNF529 | ZNF529-AS1 | ZNF530 | ZNF532 | ZNF534 | ZNF536 | ZNF540 | ZNF541 | ZNF542P | ZNF543 | ZNF544 | ZNF546 | ZNF547 | ZNF548 | ZNF549 | ZNF550 | ZNF551 | ZNF552 | ZNF554 | ZNF555 | ZNF556 | ZNF557 | ZNF558 | ZNF559 | ZNF559-ZNF177 | ZNF560 | ZNF561 | ZNF561-AS1 | ZNF562 | ZNF563 | ZNF564 | ZNF565 | ZNF566 | ZNF566-AS1 | ZNF567 | ZNF568
