SLC5A12: A Protein Involved in Neurological Disorders (G159963)

Target Name: SLC5A12

NCBI ID: G159963

SLC5A12

SLC5A12: A Protein Involved in Neurological Disorders

SLC5A12 (MGC52019) is a protein that is expressed in various tissues throughout the body. It is a member of the SLC family, which is known for its ability to transport a wide variety of molecules across cell membranes. SLC5A12 is primarily expressed in the brain, and has been shown to play a role in the development and progression of various neurological disorders, including Alzheimer's disease.

One of the key functions of SLC5A12 is its role in the regulation of the outflow of water and solutes into and out of cells. This is accomplished through its ability to interact with and modulate the activity of several different proteins, including the anion transport protein (ATP) and the water transport protein (WT).

SLC5A12 has also been shown to play a role in the regulation of ion and water homeostasis in the brain. It has been shown to help maintain the levels of ions and water in the brain, and to play a role in the regulation of the brain's water balance.

In addition to its role in ion and water homeostasis, SLC5A12 has also been shown to play a number of other important roles in the development and progression of neurological disorders. For example, it has been shown to be involved in the development of neurodegenerative diseases, including Alzheimer's disease. It has also been shown to be involved in the development of other neurological disorders, such as Parkinson's disease and multiple sclerosis.

Given its involvement in a wide range of important functions in the brain, SLC5A12 is an attractive target for drug development. Researchers are currently working to develop small molecules that can modulate the activity of SLC5A12, with the goal of using these drugs to treat a variety of neurological disorders.

In addition to its potential as a drug target, SLC5A12 is also an important biomarker for a number of neurological disorders. For example, it has been shown to be an effective indicator of the severity of Alzheimer's disease, and has been used as a biomarker to track the progression of this disease in both humans and animal models.

Overall, SLC5A12 is a protein that has important roles in the development and progression of a wide variety of neurological disorders. Its potential as a drug target and biomarker make it an attractive target for further research and development.

Protein Name: Solute Carrier Family 5 Member 12

Functions: Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate (By similarity)

The "SLC5A12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC5A12 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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