SLC5A4-AS1: A Potential Drug Target and Biomarker (G110806273)

Target Name: SLC5A4-AS1

NCBI ID: G110806273

SLC5A4-AS1

Other Name(s): SLC5A4 antisense RNA 1

SLC5A4-AS1: A Potential Drug Target and Biomarker

Sodium-glucose cotransporter 5 (SLC5A4) is a gene that encodes a protein involved in the transport of sodium and glucose across cell membranes. SLC5A4 is expressed in many tissues and is involved in various physiological processes, including cell signaling, metabolism, and inflammation. Its expression has also been implicated in several diseases, including diabetes, obesity, and cancer.

Antisense RNA (ASRNA) technology has been used to identify potential drug targets and biomarkers for SLC5A4. One of the ASNAs identified using this technology is SLC5A4-AS1.

SLC5A4-AS1 is a 21-nt RNA molecule that is derived from the SLC5A4 gene. It is expressed in various tissues, including liver, pancreas, and placenta, and has been shown to be involved in the regulation of glucose metabolism.

SLC5A4-AS1 functions as an antisense RNA by binding to a specific stretch of DNA in the SLC5A4 gene. This interaction between SLC5A4-AS1 and the SLC5A4 protein can cause the protein to alter its structure and function.

SLC5A4-AS1 has been shown to play a role in the regulation of glucose metabolism by modulating the activity of several enzymes involved in the glycolytic pathway, including GLUT1, GLUT2, and GLUT4. These enzymes are involved in the breakdown of glucose to produce energy, and their activity is regulated by various factors, including insulin andekine.

SLC5A4-AS1 has also been shown to interact with the protein known as Pyruvate Carrier (PyCR), which is involved in the transport of pyruvate across the cell membrane. The interaction between SLC5A4-AS1 and PyCR has been shown to regulate the activity of PyCR and influence the amount of pyruvate produced in cells.

SLC5A4-AS1 has also been shown to play a role in the regulation of cellular processes involved in inflammation and stress. For example, it has been shown to be involved in the regulation of the production of pro-inflammatory cytokines, such as interleukin-1尾 (IL-1尾), by modulating the activity of several enzymes involved in inflammation and stress responses, including transcription factor-induced silencing (TISF) and Nrf2.

SLC5A4-AS1 has also been shown to play a role in the regulation of cellular processes involved in cell signaling and metabolism. For example, it has been shown to be involved in the regulation of cell signaling by modulating the activity of several enzymes involved in cell signaling pathways, including cell cycle-dependent kinases (CDKs) and protein kinases (PKs).

SLC5A4-AS1 has also been shown to play a role in the regulation of cellular processes involved in energy metabolism. For example, it has been shown to be involved in the regulation of cellular energy metabolism by modulating the activity of several enzymes involved in the tricarboxylic acid (TCA) cycle and the citric acid cycle, including succinyl-CoA synthetase (SCS) and isocitrate dehydrogenase (PDH).

SLC5A4-AS1 has also been shown to play a role in the regulation of cellular processes involved in cell adhesion and migration. For example, it has been shown to be involved in the regulation of cell adhesion by modulating the activity of several enzymes involved in cell adhesion and migration, including cadherin and integrin.

SLC5A4-AS1 has also been shown to play a role in the regulation of cellular processes involved in cell signaling and metabolism. For example, it has been shown to be involved in the regulation of cellular signaling by modulating the activity of several enzymes involved in cell signaling pathways, including cell cycle-dependent kinases (CDKs) and protein kinases (PKs).

In conclusion, SLC5A4-AS1 is a promising drug target and biomarker for several diseases, including diabetes, obesity, and cancer. Its interaction with the SLC5A4 protein and its role in the regulation of glucose metabolism, inflammation, stress, and energy metabolism suggest that it may be a useful target for therapeutic interventions aimed at treating these diseases. Further research is needed to confirm its potential as a drug target and biomarker.

Protein Name: SLC5A4 Antisense RNA 1

The "SLC5A4-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC5A4-AS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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