Cyclophilins (nonspecified subtype)
Review Report on Cyclophilins (nonspecified subtype) Target / Biomarker Content of Review Report on Cyclophilins (nonspecified subtype) Target / Biomarker
Cyclophilins (nonspecified subtype)

Related Diseases

1) Congenital Myopathy
Batten-Turner Congenital Myopathy, also known as congenital myopathy, is related to myopathy, congenital, bailey-bloch and king-denborough syndrome. An important gene associated with Batten-Turner Congenital Myopathy is MYH7 (Myosin Heavy Chain 7), and among its related pathways/superpathways are Cardiac conduction and DREAM Repression and Dynorphin Expression. The drugs Lamotrigine and Mexiletine have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle, eye and brain, and related phenotypes are myopathy and abnormality of the nervous system

2) Stroke, Ischemic
Stroke, Ischemic, also known as cerebral infarction, is related to sneddon syndrome and brain small vessel disease 1, and has symptoms including angina pectoris, back pain and chest pain. An important gene associated with Stroke, Ischemic is F5 (Coagulation Factor V), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Diseases of hemostasis. The drugs Heparin, bovine and Nadroparin have been mentioned in the context of this disorder. Affiliated tissues include Bone and Brain, and related phenotypes are stroke and homeostasis/metabolism

3) Stroke
Cerebrovascular Disease, also known as cerebrovascular disorder, is related to basal ganglia cerebrovascular disease and stroke, ischemic, and has symptoms including headache, transient ischemic attacks, stereotypic symptoms and angina pectoris. An important gene associated with Cerebrovascular Disease is HOTAIR (HOX Transcript Antisense RNA), and among its related pathways/superpathways are Signal Transduction and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). The drugs Acetylcarnitine and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include brain, bone marrow and heart, and related phenotypes are homeostasis/metabolism and growth/size/body region

4) Asthma
Asthma, also known as chronic obstructive asthma, is related to allergic asthma and childhood-onset asthma, and has symptoms including recurring periods of wheezing, chest tightness and shortness of breath. An important gene associated with Asthma is IL13 (Interleukin 13), and among its related pathways/superpathways are Allograft rejection and Interleukin-4 and Interleukin-13 signaling. The drugs Fentanyl and Etomidate have been mentioned in the context of this disorder. Affiliated tissues include Lung, smooth muscle and skin, and related phenotypes are asthma and bronchoconstriction

5) Myocardial Infarction
Myocardial Infarction, also known as heart attack, is related to lipoprotein quantitative trait locus and cardiovascular system disease, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Myocardial Infarction is MIAT (Myocardial Infarction Associated Transcript), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway. The drugs Miconazole and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include Bone and Limb.

6) Hepatitis C, Chronic
Hepatitis C, also known as hepatitis c infection, is related to hepatitis c virus and viral infectious disease, and has symptoms including fever, fatigue and loss of appetite. An important gene associated with Hepatitis C is MIR122 (MicroRNA 122), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Ezetimibe and Acarbose have been mentioned in the context of this disorder. Affiliated tissues include Blood, liver and kidney, and related phenotypes are Increased JFH-1 genotype 2a Hepatitis C virus (HCV) infection and immune system

7) Duchenne Muscular Dystrophy
Muscular Dystrophy, Duchenne Type, also known as duchenne muscular dystrophy, is related to muscular dystrophy, becker type and facioscapulohumeral muscular dystrophy 1, and has symptoms including waddling gait and weakness. An important gene associated with Muscular Dystrophy, Duchenne Type is DMD (Dystrophin), and among its related pathways/superpathways are Cell differentiation - expanded index and miRNAs involvement in the immune response in sepsis. The drugs Carvedilol and Ramipril have been mentioned in the context of this disorder. Affiliated tissues include Adipose and Umbilical Cord, and related phenotypes are scoliosis and respiratory insufficiency

8) Periodontitis
Periodontitis, also known as chronic pericementitis, is related to periodontitis, chronic and periodontitis, aggressive, 1, and has symptoms including leukorrhea and purulent discharge. An important gene associated with Periodontitis is CDKN2B-AS1 (CDKN2B Antisense RNA 1), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Sodium fluoride and Menthol have been mentioned in the context of this disorder. Affiliated tissues include bone, neutrophil and endothelial, and related phenotypes are homeostasis/metabolism and immune system

9) Leukemia
Leukemia, also known as leukaemia, unspecified, without mention of remission, is related to myeloid leukemia and leukemia, chronic myeloid, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Leukemia is MIR27A (MicroRNA 27a), and among its related pathways/superpathways are NF-kappaB Signaling and Imatinib and chronic myeloid leukemia. The drugs Azacitidine and Decitabine have been mentioned in the context of this disorder. Affiliated tissues include myeloid, bone marrow and t cells, and related phenotypes are Increased HDAC inhibitor resistance and endocrine/exocrine gland

10) Scleroderma
Systemic Scleroderma, also known as scleroderma, is related to scleroderma, familial progressive and diffuse cutaneous systemic sclerosis, and has symptoms including exanthema, pruritus and hidebound skin. An important gene associated with Systemic Scleroderma is TSIX (TSIX Transcript, XIST Antisense RNA), and among its related pathways/superpathways are Akt Signaling and PAK Pathway. The drugs Metronidazole and Tadalafil have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and heart, and related phenotypes are arthralgia and myalgia

11) Rheumatoid Arthritis
Rheumatoid Arthritis, also known as ra, is related to arthritis and psoriatic arthritis, and has symptoms including back pain, muscle cramp and sciatica. An important gene associated with Rheumatoid Arthritis is PTPN22 (Protein Tyrosine Phosphatase Non-Receptor Type 22), and among its related pathways/superpathways are NF-kappaB Signaling and Genes associated with the development of rheumatoid arthritis. The drugs Entecavir and Alendronic acid have been mentioned in the context of this disorder. Affiliated tissues include Cartilage, joint and bone, and related phenotypes are joint stiffness and fatigue

12) Conjunctivitis, Allergic
Allergic Conjunctivitis, also known as perennial allergic conjunctivitis, is related to vernal keratoconjunctivitis and giant papillary conjunctivitis. An important gene associated with Allergic Conjunctivitis is HRH1 (Histamine Receptor H1), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Hyaluronic acid and Tacrolimus have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and thymus, and related phenotypes are homeostasis/metabolism and immune system

13) Muscular Dystrophy
Muscular Dystrophy, also known as muscular dystrophies, is related to limb-girdle muscular dystrophy and muscular dystrophy, limb-girdle, autosomal recessive 2, and has symptoms including back pain, muscle cramp and myoclonus. An important gene associated with Muscular Dystrophy is DMD (Dystrophin), and among its related pathways/superpathways are DREAM Repression and Dynorphin Expression and Acute viral myocarditis. The drugs Carvedilol and Ramipril have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle, bone marrow and brain, and related phenotypes are no effect and no effect

14) Thrombosis
Complement Hyperactivation, Angiopathic Thrombosis, and Protein-Losing Enteropathy, also known as chaple, is related to blood group, cromer system and protein-losing enteropathy. An important gene associated with Complement Hyperactivation, Angiopathic Thrombosis, and Protein-Losing Enteropathy is CD55 (CD55 Molecule (Cromer Blood Group)). The drugs Dabigatran and Norethisterone have been mentioned in the context of this disorder. Affiliated tissues include liver, whole blood and endothelial, and related phenotypes are thrombocytosis and hepatomegaly

15) Psoriasis
Psoriasis is related to psoriasis 7 and psoriasis 10, and has symptoms including exanthema, pruritus and psoriasiform rash. An important gene associated with Psoriasis is MIR203A (MicroRNA 203a), and among its related pathways/superpathways are miRNAs involvement in the immune response in sepsis and Cell differentiation - expanded index. The drugs Metformin and Vedolizumab have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and endothelial.

The "Cyclophilins (nonspecified subtype) Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about Cyclophilins (nonspecified subtype) comprehensively including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

11beta-Hydroxysteroid Dehydrogenase | 14-3-3 Protein | 15-Lipoxygenase | 17-beta-Hydroxysteroid dehydrogenase | 28S ribosomal subunit, mitochondrial | 3-Ketoacyl-CoA Thiolase (3-KAT) | 39S ribosomal subunit, mitochondrial | 4EHP-GYF2 complex | 5-Hydroxytryptamine Receptor | 5-Hydroxytryptamine Receptor 1 (5-HT1) | 5-Hydroxytryptamine Receptor 2 (5-HT2) | 60S Ribosome | 9-1-1 cell-cycle checkpoint response complex | A-Kinase Anchor Proteins | A1BG | A1BG-AS1 | A1CF | A2M | A2M-AS1 | A2ML1 | A2MP1 | A3GALT2 | A4GALT | A4GNT | AAAS | AACS | AACSP1 | AADAC | AADACL2 | AADACL2-AS1 | AADACL3 | AADACL4 | AADACP1 | AADAT | AAGAB | AAK1 | AAMDC | AAMP | AANAT | AAR2 | AARD | AARS1 | AARS2 | AARSD1 | AASDH | AASDHPPT | AASS | AATBC | AATF | AATK | ABALON | ABAT | ABCA1 | ABCA10 | ABCA11P | ABCA12 | ABCA13 | ABCA17P | ABCA2 | ABCA3 | ABCA4 | ABCA5 | ABCA6 | ABCA7 | ABCA8 | ABCA9 | ABCB1 | ABCB10 | ABCB11 | ABCB4 | ABCB5 | ABCB6 | ABCB7 | ABCB8 | ABCB9 | ABCC1 | ABCC10 | ABCC11 | ABCC12 | ABCC13 | ABCC2 | ABCC3 | ABCC4 | ABCC5 | ABCC6 | ABCC6P1 | ABCC6P2 | ABCC8 | ABCC9 | ABCD1 | ABCD2 | ABCD3 | ABCD4 | ABCE1 | ABCF1 | ABCF1-DT | ABCF2 | ABCF3 | ABCG1 | ABCG2

Disease Target / Biomarker