Disease

Psoriasis

Review Report on Psoriasis Target / Biomarker Content of Review Report on Psoriasis Target / Biomarker
Psoriasis


About the Disease
Psoriasis is related to psoriasis 7 and psoriasis 10, and has symptoms including exanthema, pruritus and psoriasiform rash. An important gene associated with Psoriasis is MIR203A (MicroRNA 203a), and among its related pathways/superpathways are miRNAs involvement in the immune response in sepsis and Cell differentiation - expanded index. The drugs Metformin and Vedolizumab have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and endothelial.

Common Targets
G27175 | G1232 | Interleukin-1 receptor-associated kinase (IRAK) (nonspecified subtype) | G11255 | G6097 | G3815 | G5478 | G8986 | G3066 | G353132 | G2706 | P16683 | G7223 | G353133 | G695 | G400757 | Na+/H+ Exchanger (NHE) (nonspecified subtype) | Interferon-alpha (IFN-alpha) (nonspecified subtype) | G7248 | G3091 | Serine/threonine-protein kinase (PAK) (nonspecified subtype) | G387082 | G4157 | G7098 | G50616 | G90865 | G113 | G595 | Carbonic Anhydrase (nonspecified subtype) | G6870 | G22823 | G2826 | G10892 | G774 | G2335 | G11091 | G3320 | G151306 | G7133 | G256076 | G57124 | C-C chemokine receptor (nonspecified subtype) | P5859 | G407035 | G100996941 | G9536 | G399669 | G7040 | G197259 | G102724156 | G105372988 | G120892 | G3491 | G3557 | G1445 | G387103 | G23569 | G84465 | G26525 | G8651 | G5650 | G3294 | G1295 | G643749 | P5760 | Interleukin 17 (nonspecified subtype) | G84814 | G3133 | G353143 | P16092 | G1436 | P5683 | P5755 | G22979 | G10742 | G1021 | G9170 | G11045 | G207 | G11201 | Carnitine O-Palmitoyltransferase 1 (CPT-1) (nonspecified subtype) | G6865 | G27178 | G115019 | Tyrosine-Protein Kinases Src (nonspecified subtype) | G389208 | P8262 | G4615 | G150280 | G4008 | G51561 | G9833 | G139065 | G3738 | G4306 | G5163 | G5789 | G353144 | G923 | G2150 | G3447 | G2915 | G1991 | G7099 | G27245 | G558 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | G353145 | G6768 | G10533 | G10499 | Ribonucleoside-diphosphate reductase | G406 | G23293 | G5142 | G10389 | G10865 | P48180 | G6445 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | G7150 | G84648 | G1019 | G105379664 | G1235 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | G673 | G682 | G4986 | G3551 | G3559 | G7376 | G4842 | G5271 | G4988 | G1636 | G51562 | G57493 | G2162 | Inhibitor of Apoptosis Proteins (IAPs) (nonspecified subtype) | Folate Receptor (nonspecified subtype) | G366 | G6722 | G471 | G10800 | Cyclophilins (nonspecified subtype) | Interleukin-1 (nonspecified subtype) | G79755 | G84876 | G5914 | G63826 | Cyclin-dependent kinase (nonspecified subtype) | Protein kinase C (nonspecified subtype) | G8722 | G2280 | G23224 | G25818 | G105375508 | G1269 | G241 | G100137047 | G9212 | G338567 | P16512 | G7295 | G85463 | G100302280 | G105373399 | G10866 | G64167 | P5684 | G1589 | G6778 | G728409 | G10536 | G5321 | G5578 | G6402 | G151 | G4049 | G191 | G4331 | G4780 | G5029 | G23765 | G541472 | G5465 | G2312 | G598 | G6093 | G6197 | Eukaryotic translation initiation factor 2-alpha kinase (nonspecified subtype) | G6702 | G10964 | G1503 | G1586 | G1950 | G448834 | G10745 | G3459 | G59341 | G1432 | G3660 | Calcium channel (nonspecified subtype) | G7297 | P15317 | G3932 | G57134 | G65250 | G1813 | G1902 | G4314 | G10320 | G3326 | G6705 | G6793 | G2100 | G727 | G5159 | G842 | G864 | G5604 | G239 | G969 | G3428 | Alpha-2 Adrenergic receptors (nonspecified subtype) | G4921 | G818 | G100526783 | G11009 | P12327 | C-X-C Chemokine Receptor CXCR1/CXCR2 (IL-8 Receptor) (nonspecified subtype) | G1520 | G660 | G29949 | HER (erbB) (nonspecified subtype) | G6046 | Phospholipase A2 (nonspecified subtype) | G2065 | G3106 | G10062 | G107987304 | G6352 | P6463 | DNA Topoisomerase II (nonspecified subtype) | G4128 | G7224 | G5164 | G1020 | G1233 | G3566 | G6319 | G5600 | Lipoxygenase (nonspecified subtype) | G5291 | G282618 | G91966 | Chymotrypsin (nonspecified subtype) | G613 | G360 | G6480 | G22839 | G8537 | G54901 | G105375716 | G3872 | G1723 | G23476 | G5293 | G160140 | G6821 | G7325 | G9817 | G1543 | G4026 | G23228 | G49860 | G3429 | G79054 | G10846 | G3156 | P5761 | G1514 | G7161 | G3350 | G3383 | G1457 | G2357 | G30009 | G3123 | G8600 | G5535 | G331 | Integrin Receptor (nonspecified subtype) | G1475 | G415116 | G204010 | G9692 | G6530 | G4321 | G79092 | G153830 | G195814 | G10673 | G960 | G57396 | G134 | G4855 | G23411 | G2475 | G84501 | G2618 | G283234 | Actin related protein 2/3 complex | G93974 | G3065 | G3594 | G64127 | Phospholipase C (nonspecified subtype) | G7189 | G929 | G6510 | G6868 | G5753 | G1268 | G8698 | G5481 | G5533 | G105371082 | G56244 | G57144 | Glutamate Transporter (nonspecified subtype) | G100313781 | G383 | G5468 | G9020 | G942 | G11214 | G3952 | P28492 | P5614 | G5460 | G914 | G3577 | G7465 | G27189 | G105377876 | G3783 | G4609 | G100506757 | G1859 | G285 | Raf kinase (nonspecified subtype) | G2272 | G2324 | G51393 | G8626 | G8828 | G8856 | G55905 | G11019 | G3290 | G1490 | Oxysterols receptor LXR (nonspecified subtype) | G100287329 | G114609 | G6424 | P6320 | Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype) | G4792 | G4916 | G54535 | G962 | P16126 | G728642 | G84720 | Tyrosine Kinase (nonspecified subtype) | G22846 | G5966 | Gap junction Connexin ( (nonspecified subtype) | G378805 | G6648 | G400955 | G4521 | G729230 | G7412 | G80003 | G5742 | Adenylate Cyclase (nonspecified subtype) | G1803 | G7334 | G831 | G841 | G5595 | G105373891 | G3375 | P24881 | G4137 | G7514 | G85407 | G2876 | P5762 | G7272 | G7442 | G5467 | G4170 | G54207 | G140609 | G3689 | G309 | G10797 | G163351 | G2214 | G102724539 | G3105 | G9732 | G135 | G3600 | G150 | G400957 | G7052 | G100 | G9429 | G590 | G6850 | G4440 | Histone acetyltransferase (HAT) (nonspecified subtype) | G3460 | P33249 | P34664 | G6403 | G5170 | G121260 | G5980 | G3605 | G170482 | G2321 | G10721 | P11113 | G163702 | G5770 | G3702 | G2952 | G115352 | G3480 | G1591 | G7535 | G4914 | G105378019 | G3595 | G3676 | G25833 | G581 | G116985 | Neurotrophic Tyrosine Kinase Receptor (TRK) (nonspecified subtype) | G246778 | G29785 | G9559 | G43 | G4878 | G51135 | G9261 | G92949 | P5867 | G100130476 | G3122 | STAT5 (nonspecified subtype) | P6884 | G2932 | G105375984 | G107983974 | P5833 | G6597 | P40594 | G3760 | G2147 | G7498 | G2260 | G101929401 | Uncharacterized LOC102724748 | G9448 | G64478 | G7075 | G200576 | G7124 | G284119 | G60685 | G6095 | CDK6/Cyclin D1 | G1512 | G53347 | G100129271 | G3630 | G1459 | G6573 | G163486 | G85480 | G100287722 | G55280 | G10363 | G5601 | G9623 | G9844 | G103021296 | G105378083 | G10111 | G11184 | G6754 | G836 | G84898 | G105371513 | G57577 | G60468 | G7097 | G7165 | G920 | G6279 | G4318 | G728723 | G2908 | G5580 | P5662 | G3741 | G10461 | G11156 | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | G3554 | G6773 | G1984 | G4985 | G330 | G5937 | G140 | G1725 | G23304 | G29128 | G5657 | G107984144 | Mitogen-Activated Protein Kinase (nonspecified subtype) | G284129 | G55876 | G6262 | G64409 | G152225 | G896 | G970 | G5729 | G3590 | G221895 | G107984145 | G9971 | G7128 | G80352 | G83700 | G597 | CDK1/Cyclin B | Vascular endothelial growth factor receptor (VEGFR) (nonspecified subtype) | G84162 | G8702 | P12328 | G3816 | G2833 | G9825 | Phospholipase A2, Cytosolic (nonspecified subtype) | Cysteine Protease (nonspecified subtype) | G1452 | G8608 | G107984146 | G100129662 | G55600 | sigma Receptor (nonspecified subtype) | G367 | G2033 | G2538 | G5894 | G3567 | G4153 | G2264 | G5290 | G412 | G4860 | G105376214 | G1131 | Toll-Like Receptor (nonspecified subtype) | G53831 | G54764 | G101929476 | G5915 | G4233 | G4795 | G11251 | Retinoid acid receptor (nonspecified subtype) | Sodium channel (nonspecified subtype) | G7010 | G100507098 | G5743 | Dual specificity protein kinase (CLK) (nonspecified subtype) | G1493 | G116173 | G126859 | G2064 | G27198 | G10984 | G9891 | G2166 | G285626 | G10203 | G22998 | G898 | G112744 | Elastase (nonspecified subtype) | G6256 | G387715 | G162514 | G6775 | G22918 | G10803 | G101928334 | G22806 | G54620 | Platelet-Derived Growth Factor (PDGF) (nonspecified subtype) | G1437 | Caspase (nonspecified subtype) | G5243 | G5741 | CDK2/Cyclin A | G7421 | G2322 | G5292 | G1230 | G3552 | P5753 | Serine protease (nonspecified subtype) | G4322 | G81890 | G941 | G23235 | G10239 | G55801 | G1075 | G1969 | G4846 | G5184 | G54622 | P11025 | G3558 | G5138 | G105374540 | G3784 | G1605 | G4313 | G7301 | G64806 | G1592 | G5579 | Leukotriene B4 receptor (LTB4-R) (nonspecified subtype) | G196 | G4524 | G3291 | G599 | G6532 | G6583 | G105371920 | Sterol O-acyltransferase (ACAT) (nonspecified subtype) | G6096 | G64332 | G2246 | G79789 | G5787 | G6281 | P33717 | G80018 | Tryptase (nonspecified subtype) | G165140 | G8019 | G25854 | G53832 | G284217 | G5605 | G56603 | G57511 | G6688 | G8654 | G4067 | G23274 | G26191 | G2869 | G5979 | G151888 | Janus Kinase (nonspecified subtype) | G10320 | G3579 | G53637 | G8832 | G9853 | G3586 | G64135 | G3791 | G1786 | G2358 | G51347 | G55915 | G9450 | G6513 | G5156 | G2638 | G11124 | G51752 | G10188 | G3592 | G2212 | G3899 | G50940 | G54106 | G8877 | G335 | G7298 | G50508 | G27161 | G9475 | G5745 | G3454 | G8808 | G55423 | G672 | G1956 | G8638 | G1024 | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | G9760 | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 (nonspecified protein) | G5008 | G101928376 | G406938 | G112755 | G114904 | G3458 | G64499 | G1513 | G4155 | G23463 | G10988 | G116362 | Cyclooxygenase (COX) (nonspecified subtype) | G4843 | G3269 | CDK2/Cyclin A2 | G4907 | G101929727 | G22861 | G5141 | G5228 | G54798 | G10135 | G121391 | CDK6/Cyclin D3 | G6257 | G5588 | G55917 | G6869 | G7428 | G4853 | G8989 | G55607 | G10296 | P34548 | G723961 | G7941 | G56288 | G1080 | G9966 | Cyclin A (nonspecified subtype) | G1234 | G125893 | Histone deacetylase (nonspecified subtype) | G177 | G1889 | G7547 | G5696 | G3115 | G332 | G59067 | G1387 | Cyclin-dependent kinase inhibitor (nonspecified subtype) | G4088 | G213 | G5532 | G2944 | Large Conductance BK(Ca) Potassium Channel (Maxi K+ Channel) (nonspecified subtype) | Hypoxia-Inducible Factor Prolyl Hydroxylase (nonspecified subtype) | G728 | G7422 | G3292 | G1240 | Chemokine receptor (nonspecified subtype) | G1588 | G80270 | P13024 | G940 | G5781 | Sterol Regulatory Element-Binding Protein (nonspecified subtype) | G1839 | G100529240 | G5534 | G2950 | G51310 | G834 | G116379 | Gap Junction Protein (nonspecified subtype) | G340061 | Angiotensin receptor (AT) (nonspecified subtype) | G1508 | G79068 | G11127 | G1719 | P24924 | P5758 | G50604 | G2524 | Nitric oxide synthase (NOS) (nonspecified subtype) | G3075 | G3570 | G4363 | G10318 | G338442 | G6810 | G7168 | G81930 | G11035 | G5406 | G285834 | G55856 | G10644 | G6347 | Retinoid RXR receptor (nonspecified subtype) | G3707 | G6258 | G2146 | G25865 | G56729 | G117194 | G3654 | G8174 | G11103 | G238 | P16740 | P29419 | G64840 | G58499 | G347404 | G348 | G169026 | G240 | P5678 | G4012 | G23315 | G3565 | G51185 | G55770 | G10989 | G983 | Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype) | G5916 | G3766 | G2935 | G10665 | G596 | Dual Specificity Mitogen-Activated Protein Kinase Kinase (MEK) (nonspecified subtype) | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | G7132 | G29110 | G23410 | G290 | G930 | 11beta-Hydroxysteroid Dehydrogenase (nonspecified subtype) | G64115 | G10758 | G5788 | G1431 | G3718 | Mitogen-activated protein kinase (JNK) (nonspecified subtype) | G7169 | G100507436 | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype) | G5972 | Parathyroid Hormone Receptors (PTHR) (nonspecified subtype) | G3553 | Collagenase (nonspecified subtype) | G4129 | G8737 | G440970 | G1499 | G7015 | G2247 | G3716 | G1901 | G25 | G5347 | G117196 | G3569 | G4048 | G100124700 | G5445 | G3667 | G5294 | G105375015 | G3107 | G5737 | NADPH Oxidase (nonspecified subtype) | G1022 | G90861 | G9290 | G9641 | G3596 | G90134 | G55799 | G3455 | G124626 | G3606 | G6928 | G7294 | G51284 | G114548 | G58985 | G59340 | G3481 | G2169 | G149233 | G4953 | G3576 | G6311 | G6934 | G23387 | G51214 | G3717 | G6891 | G50943 | G23643 | G4803 | G3162 | G197131 | G105379053 | IL-17 Receptor (nonspecified subtype) | G4312 | G5266 | G84561 | G53919 | P11049 | G8639 | P29647 | Peptidyl arginine deiminase (PAD) (nonspecified subtype) | G6714 | G6790 | G2010 | G757 | G3119 | Glutathione peroxidase (nonspecified subtype) | G3490 | G1369 | G5724 | G6331 | G63892 | G676 | G10413 | G127623 | G4915 | Superoxide dismutase (SOD) (nonspecified subtype) | G1186 | G7096 | G57178 | G3202 | CDK4/Cyclin D3 | G50615 | G246 | G84871 | G10666 | G6647 | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | G4790 | G11040 | P16165 | G152 | G2001 | G8767 | G10579 | G6774 | G2113 | G79866 | G23586 | G3882 | G329 | Phosphodiesterase (nonspecified subtype) | G441108 | G5144 | G6401 | G3684 | G43847 | G22900 | G5133 | G8935 | G90355 | P17896 | G6894 | G4486 | G8618 | G8535 | Acetyl-CoA Carboxylases (ACC) (nonspecified subtype) | Sphingosine kinase (nonspecified subtype) | G6696 | G102 | G55328 | G959 | CDK4/Cyclin D1 | G3949 | G10013 | P6058 | G4162 | G1017 | G57521 | Cyclin B (nonspecified subtype) | G3593 | G51311

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•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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Deficiency | Sulfite Oxidase Deficiency | Superficial Spreading Melanoma | Supravalvular Aortic Stenosis | Sweet Syndrome | Swine Influenza | Syncope | Syndactyly | Synovitis | Synpolydactyly | Syphilis | Systemic Lupus Erythematosus | Systemic Mastocytosis | T-cell Chronic Lymphocytic Leukemia | T-cell Leukemia | T-cell Lymphoma, Subcutaneous Panniculitis-like | T-cell Prolymphocytic Leukemia | Takayasu's Arteritis | Takenouchi-Kosaki Syndrome | Takotsubo Cardiomyopathy | Tangier Disease | Tardive Dyskinesia | TARP Syndrome | Tatton-Brown-Rahman Syndrome | Tay-Sachs Disease | Temporal Lobe Epilepsy | Temtamy Preaxial Brachydactyly Syndrome | Tendinitis | Tendinopathy | Tenosynovial Giant Cell Tumor | Teratozoospermia | Tetanus | Tetraplegia | Thalassemia | Thalassemia, Beta | Thanatophoric Dysplasia | Thanatophoric Dysplasia Type 1 | Thin Basement Membrane Disease | Thrombasthenia | Thrombocythemia, Essential | Thrombocytopenia | Thromboembolism | Thrombophilia | Thrombophlebitis | Thrombosis | Thrombotic Microangiopathy | Thymoma, Malignant | Thyroid Dysgenesis | Thyroid Dyshormonogenesis | Thyroid Hormone Resistance | Thyroiditis | Thyroiditis, Autoimmune | Thyrotoxic Periodic Paralysis | Tibial Muscular Dystrophy | Tic Disorder | Tietze Syndrome | Tinea | Tinea Versicolor | Tonsillitis | Torticollis | Toxic Epidermal Necrolysis | Toxoplasmosis | Traboulsi Syndrome | Tracheal Disorders | Trachoma | Transcobalamin Deficiency | Transient Bullous Dermolysis Of The Newborn | Transthyretin-related Amyloidosis | Treacher Collins Syndrome | Tremor | Tricho-hepato-enteric Syndrome | Trichomegaly | Trichorhinophalangeal Syndrome | Trichothiodystrophy | Trichotillomania | Trichuriasis | Trigonocephaly | Trimethylaminuria | Triphalangeal Thumb-polysyndactyly Syndrome | Triple A Syndrome | Trismus-pseudocamptodactyly Syndrome | Tuberculosis | Tuberculous Meningitis | Tularemia | Tumoral Calcinosis | Turner's Syndrome | Twin-to-twin Transfusion Syndrome | Tylosis With Esophageal Cancer | Tyrosine Hydroxylase Deficiency | Tyrosinemia | Tyrosinemia Type 1 | Tyrosinemia Type 2 | Ulcerative Colitis | Unverricht-Lundborg Syndrome | Urea Cycle Disorder | Uremia | Uremic Pruritus | Ureteropelvic Junction Obstruction | Urethritis | Urofacial Syndrome | Urolithiasis | Urticaria | Usher Syndrome | Usher Syndrome Type I | Usher Syndrome Type II | Usher Syndrome Type IIC | Usher Syndrome Type III | Uterine Leiomyoma | Uveitis | Uveitis, Anterior | VACTERL Association | VACTERL/VATER Association | Vaginitis | Van Der Knaap Disease | Varices | Varicocele | Vascular Calcification | Vascular Cognitive Impairment | Vasculitis | Veno-occlusive Disease | Venous Insufficiency | Ventricular Septal Defect | Vertebrobasilar Insufficiency | Vertigo | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Vestibular Disease | VEXAS Syndrome | Vici Syndrome | Viral Meningitis | Vitamin A Deficiency | Vitamin B12 Deficiency | Vitamin D Deficiency | Vitamin K Deficiency | Vitelliform Macular Dystrophy | Vitiligo | Vitreoretinal Degeneration, Snowflake Type | Vitreoretinopathy, Proliferative | Vogt-Koyanagi-Harada Syndrome | Von Hippel-Lindau Disease | Von Willebrand Disease | Vulvovaginitis | Waardenburg Syndrome | Waardenburg Syndrome Type 1 | Waardenburg Syndrome Type 2 | Waardenburg Syndrome Type 2A | Waardenburg Syndrome Type 2E | Waardenburg Syndrome Type 4 | Waardenburg Syndrome Type 4A | Wagner Disease | WAGR Syndrome | Waldenstrom Macroglobulinemia | Walker-Warburg Syndrome | Warsaw Breakage Syndrome | Weill-Marchesani Syndrome | Werner's Syndrome | Whipple's Disease | Wieacker-Wolff Syndrome | Wiedemann-Steiner Syndrome | Williams Syndrome | Wilson's Disease | Wiskott-Aldrich Syndrome | Withdrawal Syndrome | Wolcott-Rallison Syndrome | Wolff-Parkinson-White Syndrome | Wolfram Syndrome