Gap junction Connexin ( (nonspecified subtype) Related Diseases

Gap junction Connexin ( (nonspecified subtype)

Related Diseases

1) Migraine
Migraine with or Without Aura 1, also known as migraine, is related to familial hemiplegic migraine and migraine without aura, and has symptoms including back pain, headache and hemiplegia. An important gene associated with Migraine with or Without Aura 1 is NOTCH3 (Notch Receptor 3), and among its related pathways/superpathways are Type II diabetes mellitus and Cellular roles of Anthrax toxin. The drugs Mineral oil and Betamethasone have been mentioned in the context of this disorder. Affiliated tissues include brain, pituitary and cortex, and related phenotypes are photophobia and vomiting

2) Diabetes Type 2
Type 2 Diabetes Mellitus, also known as insulin resistance, is related to diabetes mellitus and maturity-onset diabetes of the young, type 8, with exocrine dysfunction, and has symptoms including angina pectoris, tremor and equilibration disorder. An important gene associated with Type 2 Diabetes Mellitus is IRS1 (Insulin Receptor Substrate 1), and among its related pathways/superpathways are Nervous system development and Angiopoietin-like protein 8 regulatory pathway. The drugs Glipizide and Glycopyrronium have been mentioned in the context of this disorder. Affiliated tissues include Pancreas and Adipose, and related phenotypes are type ii diabetes mellitus and insulin resistance

3) Asthma
Asthma, also known as chronic obstructive asthma, is related to allergic asthma and childhood-onset asthma, and has symptoms including recurring periods of wheezing, chest tightness and shortness of breath. An important gene associated with Asthma is IL13 (Interleukin 13), and among its related pathways/superpathways are Allograft rejection and Interleukin-4 and Interleukin-13 signaling. The drugs Fentanyl and Etomidate have been mentioned in the context of this disorder. Affiliated tissues include Lung, smooth muscle and skin, and related phenotypes are asthma and bronchoconstriction

4) Fibrillation, Atrial
Atrial Fibrillation, also known as a fib - [atrial fibrillation], is related to stroke, ischemic and mitral valve stenosis, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Atrial Fibrillation is SCN5A (Sodium Voltage-Gated Channel Alpha Subunit 5), and among its related pathways/superpathways are Neuropathic Pain-Signaling in Dorsal Horn Neurons and G-Beta Gamma Signaling. The drugs Hydroxychloroquine and Isoprenaline have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and atrioventricular node, and related phenotypes are no effect and no effect

5) Myocardial Infarction
Myocardial Infarction, also known as heart attack, is related to lipoprotein quantitative trait locus and cardiovascular system disease, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Myocardial Infarction is MIAT (Myocardial Infarction Associated Transcript), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway. The drugs Miconazole and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include Bone and Limb.

6) Atopic Dermatitis
Dermatitis, Atopic, also known as atopic dermatitis, is related to allergic disease and dermatitis, atopic, 3, and has symptoms including exanthema and pruritus. An important gene associated with Dermatitis, Atopic is FLG (Filaggrin), and among its related pathways/superpathways are MIF Mediated Glucocorticoid Regulation and Cytokine Signaling in Immune system. The drugs Zinc oxide and Coal tar have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and breast, and related phenotypes are cataract and ichthyosis

7) Pain
Paine Syndrome, also known as pain disorder, is related to paroxysmal extreme pain disorder and indifference to pain, congenital, autosomal recessive. An important gene associated with Paine Syndrome is HFE (Homeostatic Iron Regulator), and among its related pathways/superpathways are Cardiac conduction and Neuropathic Pain-Signaling in Dorsal Horn Neurons. The drugs Pregabalin and Dinoprostone have been mentioned in the context of this disorder. Affiliated tissues include dorsal root ganglion, spinal cord and breast, and related phenotypes are microcephaly and spastic diplegia

8) Epilepsy
Epilepsy, also known as epilepsy syndrome, is related to epilepsy, myoclonic juvenile and childhood absence epilepsy, and has symptoms including back pain, headache and pain. An important gene associated with Epilepsy is SCN1A (Sodium Voltage-Gated Channel Alpha Subunit 1), and among its related pathways/superpathways are Neuropathic Pain-Signaling in Dorsal Horn Neurons and Neuroscience. The drugs Ethosuximide and Vigabatrin have been mentioned in the context of this disorder. Affiliated tissues include brain, temporal lobe and thalamus, and related phenotypes are nervous system and growth/size/body region

9) Neuropathy
Neuropathy, also known as peripheral neuropathy, is related to neuropathy, hereditary, with liability to pressure palsies and neuropathy, hereditary sensory and autonomic, type iia, and has symptoms including back pain, headache and neuralgia. An important gene associated with Neuropathy is DLX6-AS1 (DLX6 Antisense RNA 1), and among its related pathways/superpathways are Neural crest differentiation and EGR2 and SOX10-mediated initiation of Schwann cell myelination. The drugs Capsaicin and Mexiletine have been mentioned in the context of this disorder. Affiliated tissues include nerves, dorsal root ganglion and bone marrow, and related phenotypes are no effect and no effect

10) Rheumatoid Arthritis
Rheumatoid Arthritis, also known as ra, is related to arthritis and psoriatic arthritis, and has symptoms including back pain, muscle cramp and sciatica. An important gene associated with Rheumatoid Arthritis is PTPN22 (Protein Tyrosine Phosphatase Non-Receptor Type 22), and among its related pathways/superpathways are NF-kappaB Signaling and Genes associated with the development of rheumatoid arthritis. The drugs Entecavir and Alendronic acid have been mentioned in the context of this disorder. Affiliated tissues include Cartilage, joint and bone, and related phenotypes are joint stiffness and fatigue

11) Diabetes
Diabetes Mellitus, also known as diabetes, is related to type 2 diabetes mellitus and gestational diabetes, and has symptoms including angina pectoris, tremor and equilibration disorder. An important gene associated with Diabetes Mellitus is KCNJ11 (Potassium Inwardly Rectifying Channel Subfamily J Member 11), and among its related pathways/superpathways are Regulation of beta-cell development and Cell differentiation - expanded index. The drugs Miconazole and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include pancreas, bone marrow and kidney.

12) Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis-Parkinsonism/dementia Complex 1, also known as guam disease, is related to frontotemporal dementia and/or amyotrophic lateral sclerosis 3 and frontotemporal dementia and/or amyotrophic lateral sclerosis 2, and has symptoms including tremor, bradykinesia and abnormality of extrapyramidal motor function. An important gene associated with Amyotrophic Lateral Sclerosis-Parkinsonism/dementia Complex 1 is TRPM7 (Transient Receptor Potential Cation Channel Subfamily M Member 7), and among its related pathways/superpathways are Neuroscience and Copper homeostasis. The drugs Varenicline and Riluzole have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, spinal cord and brain, and related phenotypes are muscle weakness and dementia

13) Liver Diseases
Liver Disease, also known as liver diseases, is related to non-alcoholic fatty liver disease and fatty liver disease, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Liver Disease is MEG3 (Maternally Expressed 3), and among its related pathways/superpathways are Metabolism and Nuclear receptors meta-pathway. The drugs Perindopril and Amlodipine have been mentioned in the context of this disorder. Affiliated tissues include liver, bone marrow and kidney, and related phenotypes are Reduced mammosphere formation and liver/biliary system

14) Seborrheic Dermatitis
Seborrheic Infantile Dermatitis, also known as cradle cap, is related to seborrheic dermatitis and dermatitis. An important gene associated with Seborrheic Infantile Dermatitis is DOP1B (DOP1 Leucine Zipper Like Protein B). The drugs Ciclopirox and Ketoconazole have been mentioned in the context of this disorder. Affiliated tissues include skin and liver.

15) Thrombosis
Complement Hyperactivation, Angiopathic Thrombosis, and Protein-Losing Enteropathy, also known as chaple, is related to blood group, cromer system and protein-losing enteropathy. An important gene associated with Complement Hyperactivation, Angiopathic Thrombosis, and Protein-Losing Enteropathy is CD55 (CD55 Molecule (Cromer Blood Group)). The drugs Dabigatran and Norethisterone have been mentioned in the context of this disorder. Affiliated tissues include liver, whole blood and endothelial, and related phenotypes are thrombocytosis and hepatomegaly

16) Retinopathy, Diabetic
Microvascular Complications of Diabetes 5, also known as diabetic retinopathy, is related to microvascular complications of diabetes 1 and type 1 diabetes mellitus. An important gene associated with Microvascular Complications of Diabetes 5 is PON1 (Paraoxonase 1), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Mecobalamin and Hydroxocobalamin have been mentioned in the context of this disorder. Affiliated tissues include Eye, and related phenotypes are homeostasis/metabolism and cardiovascular system

17) Corneal Ulcer
Corneal Ulcer, also known as ulcerative keratitis, is related to conjunctivitis and pyoderma. An important gene associated with Corneal Ulcer is NGF (Nerve Growth Factor), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Amphotericin B and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include eye, bone marrow and endothelial, and related phenotypes are homeostasis/metabolism and immune system

18) Psoriasis
Psoriasis is related to psoriasis 7 and psoriasis 10, and has symptoms including exanthema, pruritus and psoriasiform rash. An important gene associated with Psoriasis is MIR203A (MicroRNA 203a), and among its related pathways/superpathways are miRNAs involvement in the immune response in sepsis and Cell differentiation - expanded index. The drugs Metformin and Vedolizumab have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and endothelial.

19) Osteoporosis
Bone Mineral Density Quantitative Trait Locus 8, also known as osteoporosis, is related to osteoporosis and bone mineral density quantitative trait locus 15, and has symptoms including angina pectoris, back pain and muscle cramp. An important gene associated with Bone Mineral Density Quantitative Trait Locus 8 is BMND8 (Bone Mineral Density Quantiative Trait Locus 8). The drugs Clobetasol and Hydrocortisone have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and spinal cord.

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