DHCR24: A Potential Drug Target and Biomarker (G1718)

Target Name: DHCR24

NCBI ID: G1718

DHCR24

DHCR24: A Potential Drug Target and Biomarker

Dihu DHCR24 is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and gastrointestinal tract. It is a member of the cryptodysmata histamine receptor 2 (DHCR) family, which is a subfamily of the G protein-coupled receptor (GPCR) family. DHCR24 is known for its role in the regulation of cellular processes that are important for maintaining the health and function of the body.

One of the key functions of DHCR24 is its role in modulating the release of histamine from mast cells and basophils. Histamine is a chemical that plays a critical role in immune and inflammatory responses, and it is released from these cells in response to certain stimuli. The release of histamine from these cells can cause a range of symptoms, including itching, swelling, and inflammation.

DHCR24 is also involved in the regulation of the growth and differentiation of epithelial cells. These cells are responsible for maintaining the lining of various body surfaces and organs, and they are critical for maintaining the body's barrier function. DHCR24 plays a role in regulating the production of new epithelial cells and in the process of cell differentiation, which is important for the development and maintenance of tissues and organs.

In addition to its role in modulating the release of histamine and regulating cell growth and differentiation, DHCR24 is also involved in the regulation of pain perception. This protein is known to interact with nociceitants, which are chemicals that are released by the body in response to pain. This interaction between DHCR24 and nociceitants is important for the regulation of pain sensitivity and the modulation of pain perception.

DHCR24 is also a potential drug target for several diseases. For example, it is a known contributor to the development of atopic dermatitis, which is a chronic skin condition that is characterized by itchy, itchy, and inflamed skin. In addition, DHCR24 is also known to be involved in the regulation of the immune response, which is important for the development and maintenance of many different diseases.

Overall, DHCR24 is a protein that is involved in a wide range of important cellular processes in the body. It is a potential drug target and biomarker for several different diseases, and further research is needed to fully understand its role in these processes.

Protein Name: 24-dehydrocholesterol Reductase

Functions: Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis (PubMed:11519011, PubMed:21671375, PubMed:25637936, PubMed:22178193). In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress (PubMed:11007892, PubMed:22010141). Also protects against amyloid-beta peptide-induced apoptosis (PubMed:11007892)

The "DHCR24 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DHCR24 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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