ENPP4: A Protein with Potential as A Drug Target and Biomarker

Target Name: ENPP4

NCBI ID: G22875

ENPP4

ENPP4: A Protein with Potential as A Drug Target and Biomarker

ENPP4 (NPP-4) is a protein that is expressed in various tissues throughout the body, including the brain, heart, kidneys, and intestines. It is a member of the ENPP family, which includes a variety of proteins that play important roles in inflammation and immune responses.

One of the functions of ENPP4 is to regulate the production of pro-inflammatory cytokines, which are molecules that play a key role in the inflammatory response. These cytokines can cause inflammation, pain, and other symptoms, and they are often used as targets for drugs that are designed to treat chronic inflammatory diseases.

In addition to its role in inflammation, ENPP4 is also thought to be involved in the regulation of cellular signaling pathways that are important for many different cellular processes. These signaling pathways can be affected by a wide variety of factors, including nutrients, toxins, and environmental conditions.

As a potential drug target, ENPP4 is being studied for its potential to treat a variety of different conditions, including chronic pain, inflammation, and autoimmune diseases. Researchers are interested in understanding how ENPP4 works at the molecular level, and how it can be manipulated to produce specific effects in different cells.

One way that researchers are studying ENPP4 is to use techniques such as live cell imaging, which allows them to visualize the activity of ENPP4 in real-time. This can help researchers to understand how the protein functions in different cellular contexts, and how it interacts with other proteins.

Another approach that researchers are using to study ENPP4 is to use biochemical assays, which allow them to measure the levels of different proteins in different cells. These assays can be used to determine the effects of drugs on ENPP4 expression and activity, and to identify potential drug targets.

In addition to its potential as a drug target, ENPP4 is also being studied as a potential biomarker for a variety of different conditions. For example, some researchers are interested in using ENPP4 as a biomarker to diagnose or monitor the progress of certain diseases, such as cancer or autoimmune disorders.

Overall, ENPP4 is a protein that is being studied for its potential as a drug target and biomarker. Its unique structure and function make it an attractive target for researchers, and its potential to treat a variety of different conditions makes it an important area of study.

Protein Name: Ectonucleotide Pyrophosphatase/phosphodiesterase 4

Functions: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors

The "ENPP4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ENPP4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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