TMEM186: A Protein Involved in Cellular Signaling, Inflammation and Stress Resistance

Target Name: TMEM186

NCBI ID: G25880

TMEM186

Other Name(s): TM186_HUMAN | Transmembrane protein 186 | transmembrane protein 186 | C16orf51

TMEM186: A Protein Involved in Cellular Signaling, Inflammation and Stress Resistance

TMEM186 (TM186_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, kidneys, and liver. It is a member of the transmembrane protein family, which means that it spans the cell membrane and extends into the cytoplasm. TMEM186 is involved in a number of cellular processes that are essential for human health, including cell signaling, inflammation, and stress resistance.

One of the key functions of TMEM186 is its role in the regulation of cellular signaling. It is a component of several signaling pathways that are involved in the regulation of cell growth, differentiation, and survival. For example, TMEM186 is involved in the TGF-β pathway, which is a well-known signaling pathway that is involved in the regulation of cell growth and differentiation. This pathway is important for the development and maintenance of tissues and organs, and it is thought to be involved in the regulation of many diseases, including cancer.

Another function of TMEM186 is its role in the regulation of inflammation. It is involved in the production and activation of immune cells, which are important for defending the body against infection and disease. TMEM186 is also involved in the regulation of inflammation-related signaling pathways, which are important for the regulation of pain and inflammation.

In addition to its role in cellular signaling and inflammation, TMEM186 is also involved in the regulation of stress resistance. It is a component of several stress response pathways, which are important for the regulation of cellular stress responses. This is important for maintaining cellular homeostasis and for the regulation of many diseases, including stress-related disorders.

TMEM186 is also a potential drug target for several diseases. For example, it is thought to be involved in the development and progression of certain types of cancer, and it is also involved in the regulation of the development and progression of cardiovascular disease. In addition, TMEM186 may be involved in the regulation of other diseases, including neurological and psychiatric disorders.

In conclusion, TMEM186 is a protein that is involved in a number of important cellular processes that are essential for human health. It is a potential drug target for several diseases and may be an important biomarker for the diagnosis and treatment of these diseases. Further research is needed to fully understand the role of TMEM186 in cellular signaling and disease, and to develop effective treatments for these conditions.

Protein Name: Transmembrane Protein 186

Functions: As part of the MCIA complex, required for efficient assembly of the mitochondrial complex I

The "TMEM186 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM186 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets