Target Name: ABLIM3
NCBI ID: G22885
Review Report on ABLIM3 Target / Biomarker Content of Review Report on ABLIM3 Target / Biomarker
ABLIM3
Other Name(s): ABLM3_HUMAN | Actin-binding LIM protein 3 (isoform 1) | KIAA0843 | Actin-binding LIM protein family member 3 | actin binding LIM protein family member 3 | abLIM-3 | AbLIM-3 | Actin-binding LIM protein 3 | Actin-binding LIM protein 3 (isoform 4) | HMFN1661 | ABLIM3 variant 2 | Actin binding LIM protein family member 3, transcript variant 5 | Actin binding LIM protein family member 3, transcript variant 2 | ABLIM3 variant 5

ABLIM3: A Potential Drug Target Or Biomarker

ABLIM3 (ABLM3_HUMAN), a protein that is expressed in various tissues of the human body, has been identified as a potential drug target or biomarker in various diseases, including cancer, cardiovascular diseases, and neurological disorders.

The protein ABLIM3 is a member of the ABL family, which is known for its role in the development and maintenance of blood vessels. ABLIM3 is expressed in various tissues of the human body, including the brain, heart, kidneys, and liver. It is also expressed in the placenta, which plays a vital role in the development and maintenance of fetal blood vessels.

One of the key functions of ABLIM3 is its role in the regulation of angiogenesis, which is the process by which new blood vessels are formed in the body. ABLIM3 is known to be involved in the regulation of angiogenesis by controlling the activity of several key genes, including the TGF-β pathway.

In addition to its role in angiogenesis, ABLIM3 is also involved in the regulation of cell signaling pathways, including the PI3K/Akt signaling pathway. This pathway is known to be involved in the regulation of various cellular processes, including cell growth, differentiation, and survival.

The identification of ABLIM3 as a potential drug target or biomarker has been the focus of ongoing research, with a focus on the development of compounds that can inhibit its activity. Several studies have shown that ABLIM3 can be targeted by small molecules, including inhibitors of the TGF-β pathway and inhibitors of the PI3K/Akt signaling pathway.

In addition to its potential use as a drug target or biomarker, ABLIM3 has also been studied for its potential utility as a diagnostic tool. The expression of ABLIM3 has been shown to be associated with the development of various diseases, including cancer, cardiovascular diseases, and neurological disorders.

The identification of ABLIM3 as a potential drug target or biomarker has the potential to lead to new treatments for a variety of diseases. Further research is needed to fully understand its role and to develop safe and effective compounds that can be used to treat or diagnose various diseases.

Protein Name: Actin Binding LIM Protein Family Member 3

Functions: May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity

The "ABLIM3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ABLIM3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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