GPR82: A GPCR Targeted for Pain, Neurotransmission and Inflammation

Target Name: GPR82

NCBI ID: G27197

GPR82

Other Name(s): G protein-coupled receptor 82 (GPR82) | Probable G-protein coupled receptor 82 | G protein-coupled receptor 82 | GPR82_HUMAN

GPR82: A GPCR Targeted for Pain, Neurotransmission and Inflammation

G protein-coupled receptors (GPCRs) are a family of transmembrane proteins that play a crucial role in cellular signaling. GPCRs are involved in various physiological processes, including sensory perception, neurotransmission, and hormone signaling. GPR82 is a GPCR that is expressed in many tissues and is involved in pain perception, neurotransmission, and other physiological processes. As a result, GPR82 has been identified as a potential drug target and a biomarker for various diseases.

GPR82 is a member of the GPCR family that includes over 700 different genes. The GPCR gene family has a well- conserved structure, with all subunits containing a transmembrane domain, a catalytic domain, and a carpal tunnel region. The transmembrane domain is responsible for the interaction between the GPCR and the intracellular signaling pathway. The catalytic domain is responsible for the interaction between the GPCR and its ligands, while the carpal tunnel region is responsible for the interaction between the GPCR and the cytoplasmic signaling pathway.

GPR82 is a GPCR that is expressed in various tissues, including the brain, heart, skeletal muscles, andTestes. GPR82 is involved in pain perception, neurotransmission, and other physiological processes. For example, GPR82 is involved in the sense of pain. Studies have shown that when GPR82 is activated, it can cause pain in animals. This suggests that GPR82 may be a potential drug target for pain management.

Another potential application of GPR82 as a drug target is its role in neurotransmission. GPR82 is involved in the neurotransmission of several neurotransmitters, including opioids, GABA, and glutamate. Studies have shown that when GPR82 is activated, it can cause increased neurotransmitter release in the brain. This suggests that GPR82 may be a potential drug target for neurotransmission disorders, such as chronic pain or neurodegenerative diseases.

GPR82 is also involved in the regulation of inflammation. Studies have shown that GPR82 can modulate the expression of pro-inflammatory genes in the immune system. This suggests that GPR82 may be a potential drug target for inflammation-related diseases, such as rheumatoid arthritis or inflammatory bowel disease.

In addition to its potential drug-targeting properties, GPR82 has also been identified as a potential biomarker for several diseases. For example, GPR82 has been used as a biomarker for cancer, neurodegenerative diseases, and pain. Studies have shown that GPR82 expression is increased in various tissues, including cancer cells and neurodegenerative diseases. This suggests that GPR82 may be a potential biomarker for these diseases and may be useful in the development of new diagnostic tests or therapies.

GPR82 is also involved in the regulation of cellular signaling pathways. Studies have shown that GPR82 can modulate the activity of several intracellular signaling pathways, including the PI3K/Akt signaling pathway and the NF-kappa-B signaling pathway. This suggests that GPR82 may be a potential drug target for diseases that are characterized by abnormal cellular signaling pathways, such as cancer, neurodegenerative diseases, and inflammatory diseases.

In conclusion, GPR82 is a GPCR that is involved in pain perception, neurotransmission, and other physiological processes. As a result, GPR82 has been identified as a potential drug target and a biomarker for various diseases. Further research is needed to fully understand the role of GPR82 in cellular signaling pathways and its potential as a drug

Protein Name: G Protein-coupled Receptor 82

Functions: Orphan receptor

The "GPR82 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GPR82 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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