TMPRSS11E: A Promising Drug Target and Biomarker for Human Chronic Pain

Target Name: TMPRSS11E

NCBI ID: G28983

TMPRSS11E

TMPRSS11E: A Promising Drug Target and Biomarker for Human Chronic Pain

Introduction

Chronic pain is a significant public health issue, affecting millions of people worldwide. The persistent nature of pain, along with its impact on quality of life, can lead to significant disability and economic costs. The pain management market is projected to reach $68.5 by billion 2027, with a compound annual growth rate (CAGR) of 5.8% from 2018 to 2027. Therefore, the development of new treatments and biomarkers for chronic pain is of great importance.

TMPRSS11E (Transiently expressed in brain by RNA-mediated regulation of pain sensitivity) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for human chronic pain. TMPRSS11E is expressed in various tissues and is involved in the regulation of pain perception. The RNA-mediated regulation of pain sensitivity is a promising approach for the development of new pain treatments, as it involves the manipulation of an essential molecule that is involved in pain perception.

Here, we will discuss the biology of TMPRSS11E, its potential as a drug target, and its role as a biomarker for human chronic pain.

Biography of TMPRSS11E

TMPRSS11E is a non-coding RNA molecule that is expressed in various tissues, including brain, heart, liver, and muscle. It is a member of the Prmr1 family, which is known for its role in the regulation of pain perception. TMPRSS11E is characterized by a unique structure, with a 150-amino acid long non-coding RNA molecule that is expressed in a stable manner in various tissues.

Expression of TMPRSS11E

TMPRSS11E is expressed in various tissues and is involved in the regulation of pain perception. It is known to be involved in the regulation of pain perception, pain modulation, and neuroinflammation. TMPRSS11E has been shown to be involved in the regulation of pain perception by modulating the activity of GABA-A伪 receptors, which are involved in the regulation of pain perception.

Potential Drug Target of TMPRSS11E

TMPRSS11E is a potential drug target for the treatment of chronic pain due to its involvement in the regulation of pain perception. GABA-A伪 receptors are known to be involved in pain perception, and TMPRSS11E has been shown to modulate the activity of these receptors. Therefore , targeting TMPRSS11E with small molecules or other therapeutic approaches may be an effective way to treat chronic pain.

Biomarker for Human Chronic Pain

TMPRSS11E has also been identified as a potential biomarker for human chronic pain. The expression of TMPRSS11E is known to be involved in the regulation of pain perception, which may be related to the intensity of pain. Therefore, measuring the expression of TMPRSS11E may be an effective way to assess the severity of chronic pain in humans.

Conclusion

TMPRSS11E is a non-coding RNA molecule that is expressed in various tissues and is involved in the regulation of pain perception. Its potential as a drug target and biomarker for human chronic pain makes it an attractive target for further research. Further studies are needed to understand the full role of TMPRSS11E in pain perception and its potential as a therapeutic approach for the treatment of chronic pain.

Protein Name: Transmembrane Serine Protease 11E

Functions: Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position

The "TMPRSS11E Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMPRSS11E comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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