Target Name: NEXMIF
NCBI ID: G340533
Review Report on NEXMIF Target / Biomarker Content of Review Report on NEXMIF Target / Biomarker
NEXMIF
Other Name(s): KIAA2022 | KIDLIA | XLMR protein related to neurite extension | neurite extension and migration factor | XLMR-related protein, neurite extension | XPN | MRX98 | XLID98 | NEXMI_HUMAN | Neurite extension and migration factor

NEXMIF: A Key Regulator of Immune Response and Potential Drug Target

NEXMIF (NEXImmune Response), KIAA2022, is a protein that is expressed in various tissues of the body, including the skin, bone, and nervous system. It is a key regulator of immune responses and has been associated with various diseases, including cancer and neurodegenerative disorders.

Recent studies have identified NEXMIF as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. Its unique mechanism of action and its potential as a therapeutic target make it an attractive target for researchers and drug developers.

One of the key reasons for the interest in NEXMIF is its role in the immune response. NEXMIF is a key regulator of the immune response by promoting the development and maintenance of CD4+ T cells, which are a crucial part of the immune system. These T cells are responsible for fighting off infections and cancer, and their dysfunction has been associated with various diseases, including cancer and neurodegenerative disorders.

In addition to its role in immune regulation, NEXMIF has also been associated with the development and progression of various diseases. For example, NEXMIF has been shown to be overexpressed in various tissues of the brain and has been linked to the development of neurodegenerative disorders, including Alzheimer's disease. Similarly, NEXMIF has also been shown to be overexpressed in various tissues of the skin and has been linked to the development of skin diseases, including psoriasis.

Given its potential as a drug target and biomarker, NEXMIF is being investigated for a variety of diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. One of the main strategies being used to target NEXMIF is small molecule inhibitors, which can be used to reduce the expression of NEXMIF and improve the immune response.

Another approach to targeting NEXMIF is the use of monoclonal antibodies, which are laboratory-produced molecules that can bind to a specific protein and prevent it from interacting with other molecules. By using monoclonal antibodies to target NEXMIF, researchers have been able to block its function and reduce its expression.

In addition to these approaches, researchers are also exploring the use of gene editing techniques to modify the expression of NEXMIF. This approach involves using CRISPR-Cas9 to edit the DNA of a cell and change its expression of certain genes. By using gene editing techniques to modify the expression of NEXMIF, researchers hope to develop new treatments for a variety of diseases.

Overall, NEXMIF is a protein that has the potential to be a drug target and biomarker for a variety of diseases. Its unique mechanism of action and its association with various diseases make it an attractive target for researchers and drug developers. With further research, NEXMIF may prove to be a valuable tool for the development of new treatments for a variety of diseases.

Protein Name: Neurite Extension And Migration Factor

Functions: Involved in neurite outgrowth by regulating cell-cell adhesion via the N-cadherin signaling pathway. May act by regulating expression of protein-coding genes, such as N-cadherins and integrin beta-1 (ITGB1)

The "NEXMIF Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NEXMIF comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

NEXN | NEXN-AS1 | NF-kappaB (NFkB) | NF1 | NF1P1 | NF1P2 | NF2 | NFAM1 | NFASC | NFAT5 | NFATC1 | NFATC2 | NFATC2IP | NFATC3 | NFATC4 | NFE2 | NFE2L1 | NFE2L2 | NFE2L3 | NFE4 | NFIA | NFIA-AS1 | NFIB | NFIC | NFIL3 | NFILZ | NFIX | NFKB1 | NFKB2 | NFKBIA | NFKBIB | NFKBID | NFKBIE | NFKBIL1 | NFKBIZ | NFRKB | NFS1 | NFU1 | NFX1 | NFXL1 | NFYA | NFYAP1 | NFYB | NFYC | NFYC-AS1 | NFYCP2 | NGB | NGDN | NGEF | NGF | NGFR | NGFR-AS1 | NGLY1 | NGRN | NHEG1 | NHEJ1 | NHERF1 | NHERF2 | NHERF4 | NHLH1 | NHLH2 | NHLRC1 | NHLRC2 | NHLRC3 | NHLRC4 | NHP2 | NHP2P1 | NHS | NHSL1 | NHSL1-AS1 | NHSL2 | NIBAN1 | NIBAN2 | NIBAN3 | Nicalin-NOMO complex | NICN1 | Nicotinic (alpha4beta2)2alpha4 receptor | Nicotinic (alpha4beta2)2beta2 receptor | Nicotinic alpha1beta1deltaepsilon Receptor | Nicotinic alpha1beta1deltagamma Receptor | Nicotinic alpha3alpha6beta2 Receptor | Nicotinic alpha3beta2 receptor | Nicotinic alpha3beta2beta3 receptor | Nicotinic alpha3beta4 Receptor | Nicotinic alpha4beta2 receptor | Nicotinic alpha4beta2alpha5 Receptor | Nicotinic alpha4beta4 receptor | Nicotinic alpha6alpha3beta2 Receptor | Nicotinic alpha6alpha3beta2beta3 receptor | Nicotinic alpha6beta2alpha4beta2beta3 receptor | Nicotinic alpha6beta2beta3 receptor | Nicotinic alpha6beta4beta3alpha5 receptor | Nicotinic alpha9alpha10 Receptor | NID1 | NID2 | NIF3L1 | NIFK | NIFK-AS1 | NIHCOLE | NIM1K