CCDC144CP: A Potential Drug Target and Biomarker (G348254)

Target Name: CCDC144CP

NCBI ID: G348254

CCDC144CP

Other Name(s): Coiled-coil domain containing 144C, pseudogene | coiled-coil domain containing 144C, pseudogene | CCDC144C

CCDC144CP: A Potential Drug Target and Biomarker

Introduction

CDC144CP, also known as coiled-coil domain containing 144C, pseudogene, is a gene located on chromosome 14 (14q34) in humans. It is a non-coding RNA molecule that has been implicated in various cellular processes, including cell adhesion, migration, and transcriptional regulation. CCDC144CP is a potential drug target and biomarker due to its unique structure and gene expression patterns.

CDC144CP's Structure and Function

The CCDC144CP gene is located on the 14th chromosome (14q34), which is one of the largest chromosomes in the human genome. It is a non-coding RNA molecule, which means that it does not code for any protein. However, it is involved in the regulation of gene expression by binding to specific DNA sequences, known as promoter or enhancer.

The CCDC144CP gene is characterized by the presence of a unique coiled-coil domain, which is a type of RNA structure that can localize to specific DNA sequences. The coiled-coil domain is responsible for the formation of a stable complex with the target DNA, allowing for efficient interaction and regulation of gene expression.

In addition to the coiled-coil domain, CCDC144CP contains a unique open reading frame, which is a sequence of DNA that is involved in the regulation of gene expression. The open reading frame is responsible for the translation of the RNA molecule into a protein.

CDC144CP's Expression and Regulation

CDC144CP is expressed in various tissues and cells in the human body, including the brain, pancreas, and heart. It is primarily expressed in the brain, where it is involved in the regulation of neural stem cell proliferation and differentiation. CCDC144CP has also been shown to be involved in the regulation of pancreatic cancer cell growth and metastasis.

CDC144CP has been shown to play a role in cell adhesion and migration. It has been shown to be involved in the regulation of tight junction formation in epithelial cells, which is important for maintaining tissue structure and barrier function.

CDC144CP has also been shown to be involved in the regulation of gene expression by binding to specific DNA sequences. It has been shown to interact with the transcription factor, p53, and enhance its transcriptional activity.

CDC144CP as a Potential Drug Target

The unique structure and function of CCDC144CP make it an attractive potential drug target. Its coiled-coil domain and open reading frame suggest that it can be targeted by small molecules or antibodies that can alter its stability or activity.

CDC144CP has been shown to play a role in the regulation of neural stem cell proliferation and differentiation. Therefore, small molecules that can inhibit its activity in these processes could be potential drugs for the treatment of neurodegenerative diseases.

CDC144CP has also been shown to be involved in the regulation of pancreatic cancer cell growth and metastasis. Therefore, small molecules that can inhibit its activity in these processes could be potential drugs for the treatment of pancreatic cancer.

Conclusion

In conclusion, CCDC144CP is a unique and promising gene that has the potential to be a drug target and biomarker. Its coiled-coil domain and open reading frame suggest that it can be targeted by small molecules or antibodies that can alter its stability or activity. Further research is needed to determine its function and potential as a drug target and biomarker.

Protein Name: Coiled-coil Domain Containing 144C, Pseudogene

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•   general information;
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•   the target screening and validation;
•   expression level;
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