Target Name: CCDC17
NCBI ID: G149483
Review Report on CCDC17 Target / Biomarker Content of Review Report on CCDC17 Target / Biomarker
CCDC17
Other Name(s): coiled-coil domain containing 17 | CCDC17 variant 1 | CCD17_HUMAN | RP4-697E16.4 | Coiled-coil domain containing 17, transcript variant 1 | Coiled-coil domain-containing protein 17 | Coiled-coil domain-containing protein 17 (isoform 1)

Unveiling the Potential Drug Target CCDC17: A Controversial Coiled-Coil Domain Containing 17

Introduction

The protein CCDC17, also known as coiled-coil domain containing 17, is a key regulator of cell adhesion and survival. It is a member of the superfamily of coiled-coil domain containing proteins (CCDSPs), which are known to play a crucial role in various cellular processes, including cell adhesion, migration, and survival. CCDC17 is highly conserved across various species, and its only encoding gene is expressed only in humans and Drosophila. Its unique 17- amino acid long cDNA sequence has elicited great interest due to its potential as a drug target or biomarker. In this article, we will explore the CCDC17 protein, its structure, function, and potential as a drug target.

Structure and Localization

The CCDC17 protein is a 17- amino acid long protein that contains a unique 17- amino acid long cDNA sequence. It has a molecular weight of 21.9 kDa and a calculated pI of 5.5. The protein is expressed in various tissues and cells, including brain , heart, liver, and cancer cells. Its expression is highly conserved across various species, and it has been shown to have similar structures in different species, suggesting that it plays a conserved function in cell biology.

CDC17 is a member of the superfamily of coiled-coil domain containing proteins (CCDSPs), which are known to play a crucial role in various cellular processes, including cell adhesion, migration, and survival. These proteins contain a unique 1-dimensional structure known as a coiled-coil, which is formed by the repetitive arrangement of amino acids in a specific order. CCDC17 is characterized by a highly conserved 17- amino acid long cDNA sequence that is responsible for its unique structure and function.

Function

The CCDC17 protein is involved in various cellular processes, including cell adhesion, migration, and survival. It is a key regulator of cell-cell adhesion, which is critical for the maintenance of tissue structure and the development of various diseases, including cancer. CCDC17 is also involved in the regulation of cell migration, which is essential for the development of tissues and organs during development and also during diseases such as cancer. In addition, CCDC17 is involved in the regulation of cell survival, which is critical for the maintenance of tissue homeostasis and the development of various diseases.

CDC17 has also been shown to play a crucial role in the regulation of cell adhesion and migration. It is a key regulator of tight junction formation, which is essential for the regulation of cell-cell adhesion. the regulation of cell migration, which is essential for the development of tissues and organs during development and also during diseases such as cancer.

Potential Drug Target

The CCDC17 protein has great potential as a drug target due to its unique structure and function. Its 17-amino acid long cDNA sequence makes it a unique target for drug development, and several studies have shown that it is a promising candidate for drug development. For instance, several studies have shown that inhibitors of CCDC17 can be effective in treating various diseases, including cancer, heart disease, and neurological diseases.

One of the promising strategies for targeting CCDC17 is the use of small molecules. Many small molecules have been shown to interact with CCDC17 and to inhibit its function. These small molecules include inhibitors of tyrosination, inhibitors of phosphorylation, and inhibitors of ubiquitination.

Another approach for targeting CCDC17 is the use of antibodies. Several antibodies have been shown to recognize and bind to CCDC17 with high affinity. These antibodies can be used to treat diseases in which CCDC17 is over-expressed or mis-expressed.

Conclusion

In conclusion, CCDC17 is a unique and conserved protein that has

Protein Name: Coiled-coil Domain Containing 17

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