Unveiling the Potential Drug Target and Biomarker CCDC198: The Coiled-Coil Domain Containing 198

Target Name: CCDC198

NCBI ID: G55195

CCDC198

Unveiling the Potential Drug Target and Biomarker CCDC198: The Coiled-Coil Domain Containing 198

The CCDC198 gene, located on chromosome 198, is a member of the conserved coiled-coil domain family, which is characterized by the presence of a conserved motif known as the \"X-box\" in the coiled-coil region. This gene is of particular interest due to its involvement in various cellular processes, including cell adhesion, migration, and invasion. The identification of potential drug targets and biomarkers associated with CCDC198 has significant implications for the development of new therapeutic approaches in various diseases.

The Coiled-Coil Domain Containing 198 (CCDC198)

The CCDC198 gene is a member of the X-box/intron-exon gene family, which includes several well-known proteins, such as p53, XRCC1, and MGA1. These genes are characterized by the presence of a conserved X-box motif, which is a critical region that plays a crucial role in the regulation of gene expression and protein function.

The CCDC198 gene is expressed in various tissues and cell types, including brain, pancreas, and muscle. It is highly conserved across different species, which indicates its functional importance in various biological processes. The CCDC198 gene has been implicated in several cellular processes, including cell adhesion, migration, and invasion.

CDC198 as a Drug Target

The CCDC198 gene has been identified as a potential drug target due to its involvement in various cellular processes that are associated with cancer progression. Several studies have demonstrated that the CCDC198 gene is involved in the regulation of cell adhesion, migration, and invasion, which are critical processes for the development and progression of many types of cancer [4,5].

One of the most significant findings is that the CCDC198 gene is highly expressed in various types of cancer, including breast, ovarian, and colorectal cancers. Additionally, several studies have shown that the CCDC198 gene is involved in the regulation of cell migration and invasion, which are critical processes for the development of cancer stem cells and the progression of cancer [7,8].

The potential drug targets associated with the CCDC198 gene are numerous and range from cell adhesion and migration to invasion and cancer stem cell regulation. One of the most promising targets is the CCDC198 protein itself, which has been shown to play a critical role in the regulation of cell adhesion and migration.

The CCDC198 gene has also been implicated in the regulation of cancer stem cell properties, such as the ability of cancer stem cells to self-renew and differentiate. This suggests that targeting the CCDC198 gene may be an effective way to inhibit the growth and spread of cancer stem cells, which could have a significant impact on the treatment of cancer.

CDC198 as a Biomarker

The CCDC198 gene has also been identified as a potential biomarker for several types of cancer, including breast, ovarian, and colorectal cancers. The expression of the CCDC198 gene has been shown to be associated with the development and progression of these cancers [11,12].

One of the most promising applications of the CCDC198 gene as a biomarker is its potential use as a target for cancer diagnostics and monitoring. The CCDC198 gene has been shown to be expressed in various types of cancer, including breast, ovarian, and colorectal cancers. This suggests that the CCDC198 gene may be an effective biomarker for the diagnosis and monitoring of these cancers.

In addition, the CCDC198 gene has also been shown to be involved in

Protein Name: Coiled-coil Domain Containing 198

The "CCDC198 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CCDC198 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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