CDCD28B: Protein Implicated in Multiple Diseases (G79140)

Target Name: CCDC28B

NCBI ID: G79140

CCDC28B

CDCD28B: Protein Implicated in Multiple Diseases

CCDC28B is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, kidneys, and intestines. It is a member of the C-typeWater box family, which is a family of proteins that are involved in a variety of cellular processes, including cell signaling, migration, and inflammation.

One of the unique features of CCDC28B is its ability to form aggregates in response to various stimuli, such as bacterial toxins or chemokines. These aggregates are composed of multiple copies of the CCDC28B protein and can be visualized using various techniques, such as immunofluorescence or electron microscopy.

CDC28B has also been shown to play a role in several diseases and conditions, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that CCDC28B is overexpressed in various types of cancer, including breast, ovarian, and prostate cancer. This suggests that targeting CCDC28B may be a promising strategy for the development of new cancer therapies.

In addition to its potential as a drug target, CCDC28B has also been shown to be a potential biomarker for several diseases. For example, studies have shown that CCDC28B is expressed in the brains of individuals with Alzheimer's disease, and that levels of CCDC28B are decreased in the brains of individuals with Parkinson's disease. This suggests that CCDC28B may be a useful biomarker for the diagnosis and treatment of these conditions.

Another potential application of CCDC28B is its role in inflammation. Studies have shown that CCDC28B is involved in the regulation of inflammation and has been shown to play a role in the development of various inflammatory diseases, including autoimmune disorders and inflammatory bowel disease.

In conclusion, CCDC28B is a protein that has been shown to play a role in a variety of cellular processes and has been implicated in several diseases and conditions. As a result, targeting CCDC28B may be a promising strategy for the development of new drugs and therapies . Further research is needed to fully understand the role of CCDC28B in these processes and to determine its potential as a biomarker.

Protein Name: Coiled-coil Domain Containing 28B

Functions: Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex

The "CCDC28B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CCDC28B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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