Introduction to CCDC185, A Potential Drug Target (G164127)

Target Name: CCDC185

NCBI ID: G164127

CCDC185

Introduction to CCDC185, A Potential Drug Target

CCDC185, also known as Coiled-Coil Domain-Containing Protein 185, is a novel drug target that has shown promise in various research studies. This article aims to explore the significant role of CCDC185 as a potential drug target or biomarker. With understanding of its structure, function, and potential therapeutic applications, scientists can harness its potential to develop effective treatments for various diseases.

The Structure and Function of CCDC185

CCDC185 is a protein that consists of 436 amino acids and is localized mainly in the cytoplasm of cells. The protein contains a coiled-coil domain, a structural motif commonly found in a variety of proteins involved in protein-protein interactions. This domain allows CCDC185 to interact with other proteins and play a crucial role in various cellular processes.

Research has suggested that CCDC185 is involved in cell cycle regulation, cellular signaling pathways, and DNA repair mechanisms. It has been identified as a component of the BRCA1-A complex, which functions in the repair of DNA double-strand breaks. This association suggests that CCDC185 plays a vital role in maintaining genomic stability and preventing the development of genetic abnormalities.

CCDC185 as a Drug Target

The intricate involvement of CCDC185 in fundamental cellular processes makes it an attractive target for drug development. A growing body of evidence suggests that modulating the activity of CCDC185 could have therapeutic effects on certain diseases.

One potential application is in the treatment of cancer. As CCDC185 is involved in DNA repair mechanisms, inhibiting its activity could sensitize cancer cells to DNA-damaging chemotherapy or radiation therapy. By preventing efficient repair of DNA damage, tumor cells become more susceptible to treatment-induced apoptosis. Additionally, CCDC185 may also have a role in promoting cell proliferation, making it a potential target to inhibit tumor growth.

Furthermore, CCDC185 has demonstrated an association with neurodegenerative disorders. Research has shown an increased expression of CCDC185 in brain tissues affected by Alzheimer's disease and Parkinson's disease. By gaining a better understanding of CCDC185's role in these diseases, it may be possible to develop targeted therapies to slow down or prevent disease progression.

CCDC185 as a Biomarker

In addition to its potential as a drug target, CCDC185 has also shown promise as a biomarker for various diseases. A biomarker is a measurable biological molecule that indicates the presence of a disease or predicts its progression. CCDC185 levels have been found to be altered in several disease conditions, making it a potential diagnostic tool.

For instance, research has identified CCDC185 as a potential biomarker in breast cancer. Studies have shown that higher CCDC185 expression is associated with more aggressive tumor behavior and poor prognosis. Measuring CCDC185 levels in breast cancer patients could help predict disease progression and tailor treatment strategies accordingly.

Moreover, CCDC185 may also serve as a biomarker for neurodegenerative disorders. Increased CCDC185 expression has been observed in the cerebrospinal fluid of patients with Alzheimer's disease. Monitoring CCDC185 levels may enable early detection of the disease and facilitate timely intervention strategies.

Conclusion

CCDC185 has emerged as a fascinating protein with tremendous potential as both a drug target and a biomarker. Its essential role in DNA repair mechanisms and cellular processes makes it an attractive target for therapeutic intervention in cancer and neurodegenerative disorders. Furthermore, the detection and measurement of CCDC185 levels provide valuable information for disease diagnosis and prognosis. Further studies are necessary to fully elucidate the mechanisms and clinical significance of CCDC185, but the current knowledge suggests that it holds great promise in advancing medical research and improving patient outcomes.

Protein Name: Coiled-coil Domain Containing 185

The "CCDC185 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CCDC185 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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