KRT8P12: A Potential Drug Target Or Biomarker (G90133)

Target Name: KRT8P12

NCBI ID: G90133

KRT8P12

Other Name(s): KRT8L2 | Keratin 8 pseudogene 12 | keratin 8 pseudogene 12

KRT8P12: A Potential Drug Target Or Biomarker

KRT8P12 (KRT8L2) is a protein that is expressed in various tissues of the body, including the brain, lungs, heart, and kidneys. It is a member of the Kallikrein-related peptidases (KRT) family, which includes several different proteins that play a role in the regulation of matrix metalloproteinases (MMPs)2.

KRT8P12 is of particular interest as a potential drug target or biomarker because of its role in the regulation of MMP2, a key mediator of tissue damage and inflammation. MMP2 is involved in the degradation of extracellular matrix (ECM) components, including collagen, which is a component of the extracellular matrix and is highly represented in tissues that are involved in injury or disease.

KRT8P12 has been shown to play a role in the regulation of MMP2 by interacting with its extracellular domain and potentially modulating its activity. This interaction between KRT8P12 and MMP2 has important implications for the regulation of tissue repair and regeneration, as well as the development of certain diseases.

One of the key functions of KRT8P12 is its role in the regulation of MMP2-dependent processes that involve the degradation of ECM components. This is accomplished through its interaction with MMP2, which allows KRT8P12 to regulate MMP2 activity and the levels of MMP2-generated products in the extracellular environment.

In addition to its role in the regulation of MMP2, KRT8P12 has also been shown to play a role in the regulation of other cellular processes that are involved in tissue repair and regeneration. For example, KRT8P12 has been shown to be involved in the regulation of cell adhesion, as well as the processes that involve the migration and survival of cells.

KRT8P12 is also of interest as a potential biomarker for certain diseases, as its levels can be affected by a variety of factors, including tissue injury or disease. For example, KRT8P12 has been shown to be elevated in the blood of individuals with certain forms of cancer, which suggests that it may be a potential biomarker for these diseases.

In conclusion, KRT8P12 is a protein that is of particular interest as a potential drug target or biomarker due to its role in the regulation of MMP2 and other cellular processes that are involved in tissue repair and regeneration. Further research is needed to fully understand the role of KRT8P12 in these processes, as well as its potential as a biomarker for certain diseases.

Protein Name: Keratin 8 Pseudogene 12

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•   general information;
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•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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