Target Name: KRT5
NCBI ID: G3852
Review Report on KRT5 Target / Biomarker Content of Review Report on KRT5 Target / Biomarker
KRT5
Other Name(s): keratin 5 | keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) | cytokeratin-5 | Cytokeratin 5 | EBS2C | CK5 | K5 | EBS2E | DDD1 | Keratin 5 | CK-5 | Cytokeratin-5 | EBS2B | EBS2A | KRT5A | EBS2 | K2C5_HUMAN | Keratin, type II cytoskeletal 5 | keratin 5, type II | EBS2D | EBS2F | DDD | 58 kda cytokeratin | 58 kDa cytokeratin | 58 Kda cytokeratin | Keratin-5 | EBS1 | Type-II keratin Kb5 | epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types | type-II keratin Kb5

KRT5: Potential Drug Target and Biomarker

KRT5 (keratin 5) is a protein that is expressed in a variety of tissues throughout the body, including hair, nails, and skin. It is a key component of the cytoskeleton, which is the structure that gives cells their shape and helps them maintain their shape during growth and development.

Recent studies have suggested that KRT5 may have a variety of potential applications as a drug target or biomarker.

One potential application of KRT5 as a drug target is its role in the development of cancer. Studies have shown that KRT5 is often overexpressed in a variety of cancer types, which suggests that targeting KRT5 may be a promising strategy for cancer treatment.

Another potential application of KRT5 as a drug target is its role in the development of skin diseases. For example, research has shown that KRT5 is overexpressed in a variety of skin conditions, including acne and psoriasis. Targeting KRT5 with drugs that can suppress its expression may be a promising strategy for treating these conditions.

In addition to its potential as a drug target, KRT5 has also been suggested as a potential biomarker for a variety of diseases. For example, KRT5 has been shown to be overexpressed in a variety of skin conditions, including acne and psoriasis. This suggests that KRT5 may be a useful biomarker for these conditions.

Overall, KRT5 is a protein that is expressed in a variety of tissues throughout the body and has been suggested as a potential drug target or biomarker in a variety of conditions. Further research is needed to fully understand its potential applications and to develop treatments based on it.

Protein Name: Keratin 5

Functions: Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity)

The "KRT5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRT5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22 | KRT8P23 | KRT8P25 | KRT8P26 | KRT8P29 | KRT8P3 | KRT8P33 | KRT8P36 | KRT8P37 | KRT8P39 | KRT8P41 | KRT8P44 | KRT8P45 | KRT8P46 | KRT8P47 | KRT8P48 | KRT8P49 | KRT8P5 | KRT8P7 | KRT8P8 | KRT8P9 | KRT9 | KRT90P | KRTAP1-1 | KRTAP1-3 | KRTAP1-4 | KRTAP1-5 | KRTAP10-1 | KRTAP10-10 | KRTAP10-11 | KRTAP10-12 | KRTAP10-2 | KRTAP10-3 | KRTAP10-4 | KRTAP10-5 | KRTAP10-6 | KRTAP10-7 | KRTAP10-8 | KRTAP10-9 | KRTAP11-1 | KRTAP12-1 | KRTAP12-2 | KRTAP12-3 | KRTAP12-4 | KRTAP13-1 | KRTAP13-2 | KRTAP13-3 | KRTAP13-4 | KRTAP15-1 | KRTAP16-1 | KRTAP17-1 | KRTAP19-1 | KRTAP19-2 | KRTAP19-3 | KRTAP19-4 | KRTAP19-5 | KRTAP19-6 | KRTAP19-7 | KRTAP19-8 | KRTAP2-1 | KRTAP2-2 | KRTAP2-3 | KRTAP2-4 | KRTAP20-1 | KRTAP20-2 | KRTAP20-3 | KRTAP20-4 | KRTAP21-1