KRT7: A Potential Drug Target and Biomarker (G3855)

Target Name: KRT7

NCBI ID: G3855

KRT7

KRT7: A Potential Drug Target and Biomarker

Keratin 7 (KRT7) is a protein that is found in the hair and scalp. It is a key component of the hair follicle and plays a crucial role in the growth and development of hair. KRT7 has been identified as a potential drug target and biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The discovery of KRT7 as a potential drug target comes from a study by the scientists at the University of California, San Diego. The study showed that the expression of KRT7 was significantly increased in the hair and scalp of individuals with the genetic condition called alopecia areata, which is a common cause of male pattern baldness. The researchers also found that blocking the activity of the KRT7 gene resulted in a significant improvement in the thickness and growth of the hair in individuals with alopecia areata.

KRT7 has also been identified as a potential biomarker for several diseases, including cancer. The scientists at the University of California, Los Angeles found that KRT7 was significantly increased in the blood samples of individuals with various types of cancer, and that these levels were associated with the severity of the cancer. The researchers also found that KRT7 levels were decreased in the urine samples of individuals with cancer, and that these levels were associated with the effectiveness of the cancer treatments.

In addition to its potential drug target and biomarker properties, KRT7 has also been shown to have several other biological functions. For example, KRT7 has been shown to play a role in cell signaling, and to regulate the growth and differentiation of hair follicles. It has also been shown to interact with several other proteins, including the protein tyrosine kinase TPK2, which is involved in cell signaling and growth.

The potential drug target and biomarker properties of KRT7 make it an attractive target for research into the treatment of hair and scalp diseases, as well as other diseases that involve cell signaling and growth. Further studies are needed to fully understand the role of KRT7 in these diseases and to develop effective treatments.

Protein Name: Keratin 7

Functions: Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7)

The "KRT7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRT7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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