KRT76: A Potential Drug Target and Biomarker (G51350)

Target Name: KRT76

NCBI ID: G51350

KRT76

KRT76: A Potential Drug Target and Biomarker

Keratin-76 (KRT76) is a protein that is expressed in the hair follicles, scalp, and nails. It is a key component of the hair follicle and plays a crucial role in the growth, development, and regression of hair. KRT76 has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The hair follicle is an essential organ that plays a vital role in maintaining the overall health and appearance of the body. The hair follicle is responsible for the production of new hair strands and the regulation of hair growth and loss. Hair loss is a common condition that affects millions of people worldwide, and it can be caused by various factors, including genetics, stress, hormonal imbalances, and environmental factors.

KRT76 is a protein that is expressed in the hair follicles and has been shown to play a crucial role in the growth, development, and regression of hair. It is composed of 19 different amino acids and has a molecular weight of 20.9 kDa. KRT76 is highly conserved across different species, which suggests that it has an important function in the hair follicle.

KRT76 has been shown to be involved in various processes that are important for hair growth and development. It has been shown to play a role in the regulation of cell proliferation, differentiation, and death. It has also been shown to be involved in the regulation of cell signaling pathways, including the TGF-β pathway.

In addition to its role in hair growth and development, KRT76 has also been shown to have potential as a drug target and biomarker for various diseases. KRT76 has been identified as a potential drug target for various neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. These conditions are characterized by the progressive loss of brain cells and progressive neurodegeneration.

KRT76 has also been shown to be involved in the development and progression of certain types of cancer, including skin cancer and breast cancer. It has been shown to be expressed in the hair follicles of individuals with certain types of cancer, which suggests that it may be a useful biomarker for these conditions.

In addition to its potential as a drug target and biomarker, KRT76 has also been shown to have potential as a diagnostic tool. The hair follicle is a simple and accessible tissue that can be used as a source of cells for laboratory studies. KRT76 can be used as a biomarker to diagnose various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

KRT76 has been shown to be involved in the regulation of cellular signaling pathways that are important for the development and progression of these diseases. For example, KRT76 has been shown to be involved in the regulation of the PI3K/AKT signaling pathway, which is involved in the regulation of cell proliferation and survival. It has also been shown to be involved in the regulation of the TGF-β pathway, which is involved in the regulation of cell signaling pathways that are important for the development and progression of neurodegenerative diseases.

In conclusion, KRT76 is a protein that is expressed in the hair follicles and has been shown to play a crucial role in the growth, development, and regression of hair. It has also been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of KRT76 in these conditions and to develop effective treatments.

Protein Name: Keratin 76

Functions: Probably contributes to terminal cornification

The "KRT76 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRT76 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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