Target Name: KRT2
NCBI ID: G3849
Review Report on KRT2 Target / Biomarker Content of Review Report on KRT2 Target / Biomarker
KRT2
Other Name(s): keratin 2, type II | cytokeratin-2e | keratin-2e | KRT2E | Keratin 2 | CK-2e | KRT2A | Epithelial keratin-2e | K2e | Keratin, type II cytoskeletal 2 epidermal | keratin 2 | Cytokeratin-2e | Keratin 2A (epidermal ichthyosis bullosa of Siemens) | Type-II keratin Kb2 | epithelial keratin-2e | Keratin-2 epidermis | K22E_HUMAN | Keratin-2e | type-II keratin Kb2 | CK 2e | KRTE | keratin-2 epidermis

KRT2: Potential Drug Targets for Hair-Related Conditions

KRT2 (keratin 2, type II) is a protein that is expressed in the hair matrix, and it is a key component of the hair follicle. The hair matrix is the protein structure that makes up the hair shaft, and it is responsible for the production and maintenance of the hair. KRT2 plays a crucial role in the production and distribution of the hair matrix, and it is a potential drug target or biomarker for various hair-related conditions.

KRT2 is a 21-kDa protein that is composed of 195 amino acid residues. It is expressed in the hair matrix and is involved in the production and distribution of the hair matrix. KRT2 is a type II transmembrane protein, which means that it is expressed in the cell body and is located in the cell membrane. It is also a non-covalent protein, which means that it is not released from the cell membrane into the surrounding tissue.

KRT2 is involved in the production and distribution of the hair matrix because it is a key component of the hair follicle. The hair follicle is the microscopic structure that is responsible for the production and distribution of the hair. The hair follicle is composed of several different cell types, including stem cells, growth factors, and protective cells. KRT2 is one of the proteins that are involved in the production and distribution of the hair matrix.

KRT2 is also involved in the regulation of the hair growth cycle. The hair growth cycle is the process by which the hair follicle grows and is transformed into a growing hair strand. The hair growth cycle is regulated by several different proteins, including KRT2. KRT2 plays a role in the regulation of the cell cycle, which is the process by which the cells divide and grow.

KRT2 is also involved in the regulation of the cell penetration of the hair matrix. The hair matrix is the protein structure that makes up the hair shaft, and it is located in the center of the hair follicle. KRT2 is involved in the regulation of the cell penetration of the hair matrix because it is a protein that is involved in the production and distribution of the hair matrix.

KRT2 is also involved in the regulation of the hair dyestylation. Hair dyestylation is the process by which the hair changes color over time. KRT2 is involved in the regulation of hair dyestylation because it is a protein that is involved in the production and distribution of the hair matrix.

KRT2 is a potential drug target or biomarker for various hair-related conditions. For example, KRT2 may be a target for therapies that are designed to stimulate hair growth, because it is involved in the production and distribution of the hair matrix. KRT2 may also be a target for therapies that are designed to treat hair loss, because it is involved in the regulation of the hair growth cycle. KRT2 may also be a target for therapies that are designed to treat hair dyestylation, because it is involved in the regulation of hair dyestylation.

In conclusion, KRT2 is a protein that is involved in the production and distribution of the hair matrix. It is a key component of the hair follicle, and it plays a crucial role in the regulation of the hair growth cycle and the hair dyestylation. As a result, KRT2 is a potential drug target or biomarker for various hair-related conditions. Further research is needed to fully understand the role of KRT2 in the hair system and to develop effective therapies for hair-related conditions.

Protein Name: Keratin 2

Functions: Probably contributes to terminal cornification (PubMed:1380918). Associated with keratinocyte activation, proliferation and keratinization (PubMed:12598329). Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity)

The "KRT2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRT2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22 | KRT8P23 | KRT8P25 | KRT8P26 | KRT8P29 | KRT8P3 | KRT8P33 | KRT8P36 | KRT8P37 | KRT8P39 | KRT8P41 | KRT8P44 | KRT8P45 | KRT8P46 | KRT8P47 | KRT8P48 | KRT8P49 | KRT8P5 | KRT8P7 | KRT8P8 | KRT8P9 | KRT9 | KRT90P | KRTAP1-1 | KRTAP1-3 | KRTAP1-4 | KRTAP1-5 | KRTAP10-1 | KRTAP10-10 | KRTAP10-11 | KRTAP10-12 | KRTAP10-2 | KRTAP10-3 | KRTAP10-4 | KRTAP10-5 | KRTAP10-6 | KRTAP10-7 | KRTAP10-8 | KRTAP10-9 | KRTAP11-1 | KRTAP12-1 | KRTAP12-2 | KRTAP12-3 | KRTAP12-4 | KRTAP13-1