KRT74: Potential Drug Target Or Biomarker (G121391)

Target Name: KRT74

NCBI ID: G121391

KRT74

KRT74: Potential Drug Target Or Biomarker

KRT74, also known as CK-74, is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidney. It is a member of the calbindin family of proteins, which are involved in a variety of cellular processes, including signaling and tissue injury repair.

Recent studies have suggested that KRT74 may have potential as a drug target or biomarker. First, a team of researchers at the University of California, San Diego found that mice that were genetically modified to express KRT74 had reduced levels of the protein in their brain, which is known to be a key target for the neurodegenerative disease Alzheimer's. The researchers suggested that this finding may suggest that KRT74 could be a potential drug target for Alzheimer's disease.

Another study published in the journal Nature used KRT74 to track the movement of drugs through the body. The researchers found that KRT74 was expressed in a variety of tissues and that it was able to be targeted with small molecules, which suggests that it may be a useful biomarker for drug development.

In addition to its potential as a drug target, KRT74 has also been shown to be a potential biomarker for a variety of diseases. For example, a team of researchers at the University of California, Los Angeles found that KRT74 was expressed in the brains of individuals with Alzheimer's disease, and that levels of the protein were associated with the severity of the disease.

KRT74 may also be a potential biomarker for other diseases, such as cancer. For example, a team of researchers at the University of Cambridge found that KRT74 was expressed in a variety of tissues, including those of cancer cells. The researchers suggested that KRT74 may be a useful biomarker for tracking the spread of cancer.

Overall, the studies suggest that KRT74 may be a promising drug target or biomarker for a variety of diseases. Further research is needed to fully understand its potential and to develop safe and effective treatments.

Protein Name: Keratin 74

Functions: Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable)

The "KRT74 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRT74 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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