Target Name: KRT32
NCBI ID: G3882
Review Report on KRT32 Target / Biomarker Content of Review Report on KRT32 Target / Biomarker
KRT32
Other Name(s): hard keratin, type I, 2 | type I cuticular hair keratin | hair keratin, type I Ha2 | Hair keratin, type I Ha2 | Keratin-32 | KRTHA2 | keratin 32, type I | keratin 32 | HA2 | hHa2 | keratin, type I cuticular Ha2 | keratin-32 | Keratin 32 | K1H2_HUMAN | K32 | keratin, hair, acidic, 2 | HKA2 | Keratin, type I cuticular Ha2

Understanding The Role of KRT32 in Hair Development and Maintenance

KRT32 (hard keratin, type I, 2) is a protein that is expressed in the hair follicles and is known for its role in the development and maintenance of the hair. The hard keratin protein is a type of cytoskeletal protein that is composed of two chains, each of which consists of approximately 250 amino acids. The two chains of hard keratin protein are held together by a disulfide bond, which is a covalent bond that is formed by the oxidation of the amino acids.

One of the unique features of hard keratin protein is its structure. Hard keratin protein has a unique three-dimensional structure that is composed of a helix-like pattern. This structure allows the protein to bind to specific DNA sequences, which is the basis for the protein's role in the development and maintenance of the hair.

KRT32 is also of interest as a potential drug target. The hair is an attractive target for drug development because of its slow growth rate and the difficulty of accessing the affected areas. Additionally, the hair is a constantly renewable resource, which makes it an attractive target for the development of new treatments.

KRT32 has also been shown to be a potential biomarker for the diagnosis of certain conditions, such as androgen-dependent and androgen-independent breast cancers. The expression of KRT32 has also been shown to be elevated in the cells of individuals with these conditions, which could make KRT32 a useful diagnostic marker.

In addition to its potential drug target and biomarker properties, KRT32 is also of interest as a potential therapeutic agent. The three-dimensional structure of KRT32 makes it a potential target for small molecules and other compounds that can modulate its function. Additionally, the protein's ability to bind to specific DNA sequences suggests that KRT32 could be a useful agent for the treatment of conditions that are caused by the buildup of DNA damage, such as cancer.

In conclusion, KRT32 is a protein that is expressed in the hair follicles and has been shown to play a role in the development and maintenance of the hair. Its unique three-dimensional structure and ability to bind to specific DNA sequences make it an attractive target for drug development and research. Additionally, KRT32 has also been shown to be a potential biomarker for the diagnosis of certain conditions and a potential therapeutic agent for the treatment of conditions caused by the buildup of DNA damage. Further research is needed to fully understand the function and potential of KRT32.

Protein Name: Keratin 32

The "KRT32 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRT32 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22 | KRT8P23 | KRT8P25 | KRT8P26 | KRT8P29 | KRT8P3 | KRT8P33 | KRT8P36 | KRT8P37 | KRT8P39 | KRT8P41 | KRT8P44 | KRT8P45 | KRT8P46 | KRT8P47 | KRT8P48 | KRT8P49 | KRT8P5 | KRT8P7 | KRT8P8 | KRT8P9 | KRT9 | KRT90P | KRTAP1-1 | KRTAP1-3 | KRTAP1-4 | KRTAP1-5 | KRTAP10-1 | KRTAP10-10 | KRTAP10-11 | KRTAP10-12 | KRTAP10-2 | KRTAP10-3 | KRTAP10-4 | KRTAP10-5 | KRTAP10-6 | KRTAP10-7 | KRTAP10-8 | KRTAP10-9 | KRTAP11-1 | KRTAP12-1 | KRTAP12-2 | KRTAP12-3 | KRTAP12-4 | KRTAP13-1 | KRTAP13-2 | KRTAP13-3 | KRTAP13-4 | KRTAP15-1 | KRTAP16-1 | KRTAP17-1 | KRTAP19-1 | KRTAP19-2 | KRTAP19-3 | KRTAP19-4 | KRTAP19-5