Discovery and Characterization of KRT36: A Potential Drug Target and Biomarker

Target Name: KRT36

NCBI ID: G8689

KRT36

Discovery and Characterization of KRT36: A Potential Drug Target and Biomarker

KRT36 (hHa6) is a protein that is expressed in various tissues of the human body, including the brain, pancreas, and gastrointestinal tract. It is a member of the heat shock protein (HSP) family and is involved in the regulation of protein synthesis and stability. KRT36 has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The discovery and characterization of KRT36

KRT36 was first identified as a heat shock protein (HSP) in the human genome using transcriptomic analysis. HSPs are proteins that are expressed in high abundance in response to increased thermal stress, such as fever or shock. KRT36 was found to be a highly expressed protein in the brain, pancreas, and gastrointestinal tract, and its expression was correlated with the expression of other HSPs, including HSP70 and HSP90.

The function of KRT36

KRT36 is involved in the regulation of protein synthesis and stability. It functions as a chaperone, helping to transport and process various proteins, including enzymes involved in cellular signaling pathways. KRT36 also plays a role in the regulation of protein stability, helping to ensure that Newly synthesized proteins are properly folded and remain in a stable state.

KRT36 is also involved in the regulation of cellular stress responses. When the body experiences stress, such as infection or inflammation, KRT36 helps to ensure that cellular stress responses are properly regulated. This is important for maintaining cellular homeostasis and preventing the development of diseases.

The potential uses of KRT36 as a drug target

KRT36 has been identified as a potential drug target for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

In cancer, KRT36 has been shown to be involved in the regulation of cell cycle progression and the execution of various cellular processes that are critical for cancer growth. For example, studies have shown that KRT36 can help to ensure that cancer cells maintain a stable cell cycle and that they are resistant to chemotherapy drugs.

In neurodegenerative diseases, KRT36 has been shown to be involved in the regulation of cellular stress responses and the execution of various cellular processes that are important for maintaining cellular homeostasis. This is important for the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In autoimmune disorders, KRT36 has been shown to be involved in the regulation of cellular stress responses and the execution of various cellular processes that are important for maintaining cellular homeostasis. This is important for the development of autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis.

KRT36 as a biomarker

KRT36 has also been identified as a potential biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because KRT36 is often expressed at higher levels in these diseases and can be used as a protein biomarker for the diagnosis and monitoring of these conditions.

For example, KRT36 has been used as a biomarker for cancer, as it has been shown to be expressed at higher levels in cancer cells compared to normal cells. This makes KRT36 a potential target for cancer therapies that target cancer cells.

KRT36 has also been used as a biomarker for neurodegenerative diseases, as it has been shown to be expressed at higher levels in the brains of individuals with neurodegenerative diseases compared to those without these conditions. This makes KRT36 a potential target for therapies that target neurodegenerative diseases.

Finally, KRT36 has also been used as a biomarker for autoimmune disorders, as it has been shown to be expressed at higher levels in the tissues of individuals with autoimmune disorders compared to those without these conditions. This makes KRT36 a potential target for

Protein Name: Keratin 36

The "KRT36 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRT36 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets