TheMC2R: A Transmembrane Protein Regulating Cell Signaling (G4158)
TheMC2R: A Transmembrane Protein Regulating Cell Signaling
TheMC2R (Mesothelin Carboxylic Acid Receptor) is a protein that is expressed in various cell types, including epithelial, mesenchymal, and neural cells. It is a transmembrane receptor that is involved in cell signaling, particularly in the regulation of cell adhesion, migration, and invasion. TheMC2R has also been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
TheMC2R was first identified in the late 1990s as a cell adhesion molecule that was expressed in epithelial cells, mesenchymal cells, and neural cells. It is composed of a extracellular domain that consists of a transmembrane region and an intracellular tail region. The transmembrane region of the MC2R consists of a catalytic domain, a hydrophobic region, and a negatively charged carboxylic acid region (CAAR). The hydrophobic region is responsible for the protein's stability and the catalytic domain is responsible for the protein's function.
TheMC2R is involved in the regulation of cell adhesion and migration, which are critical processes that play a central role in the development and progression of many diseases. During cell adhesion, the MC2R helps to regulate the formation and maintenance of tight junctions, which are a type of cell-cell adhesion that is critical for the integrity of tissues. In addition, the MC2R is also involved in the regulation of cell migration, which is critical for the development of new tissues and organs during development and wound healing.
TheMC2R has also been identified as a potential drug target for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that the MC2R is involved in the regulation of cancer cell growth and that inhibiting its function may be an effective way to treat cancer. In addition, the MC2R has also been shown to be involved in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. TheMC2R has also been identified as a potential biomarker for these diseases, as its levels have been shown to be altered in the brains of individuals with these conditions.
In addition to its potential clinical applications, the MC2R is also an important protein that is involved in the regulation of cell signaling. The MC2R plays a central role in the regulation of cell adhesion and migration, which are critical processes that are essential for the development and maintenance of tissues. The MC2R is also involved in the regulation of cell survival and proliferation, which are critical processes that are essential for the growth and development of tissues.
TheMC2R is a transmembrane protein that is involved in the regulation of cell signaling. It is expressed in various cell types, including epithelial, mesenchymal, and neural cells. The MC2R plays a central role in the regulation of cell adhesion and migration, which are critical processes that play a central role in the development and progression of many diseases. In addition, the MC2R has also been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
Protein Name: Melanocortin 2 Receptor
Functions: Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP)
The "MC2R Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MC2R comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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