Target Name: MTHFD2P7
NCBI ID: G442098
Review Report on MTHFD2P7 Target / Biomarker Content of Review Report on MTHFD2P7 Target / Biomarker
MTHFD2P7
Other Name(s): methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase pseudogene 7 | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase pseudogene 7

MTHFD2P7: A Pseudogene Enriching The Metabolism of Nucleotides and Compounds

MTHFD2P7, also known as methylenetetrahydrofolate dehydrogenase (NADP+-dependent), is a gene that encodes a protein in the folate cycle, which is a crucial molecule in the metabolism of nitrogen and the synthesis of DNA and RNA. MTHFD2P7 is primarily expressed in the liver and other tissues, and it plays a key role in the metabolism of methenyltetrahydrofolate, a coenzyme that is involved in the synthesis of DNA and RNA.

MTHFD2P7 is a pseudogene, which means that it is a genetic sequence that has the potential to produce a functional protein. The pseudogenes are often used as drug targets or biomarkers because they can be targeted by small molecules, such as drugs, to enhance their therapeutic effects.

One of the unique features of MTHFD2P7 is its dependence on NADP+, a crucial coenzyme that is involved in many cellular processes. MTHFD2P7 is an NADP+-dependent enzyme, which means that it requires NADP+ to function properly. This is important because NADP+ is a potent inhibitor of many cellular processes, including cell division, and it has been shown to have a variety of therapeutic effects, including anti-inflammatory and anti-cancer effects.

MTHFD2P7 is involved in the metabolism of methenyltetrahydrofolate, which is a coenzyme that is synthesized from the amino acids alanine, methionine, and vitamin B12. MTHFD2P7 is the enzyme that converts methenyltetrahydrofolate to 5-methyl-3-methylenediamine, which is then converted to 5-methyl-3-methylenediamine-2, which is involved in the synthesis of DNA and RNA.

MTHFD2P7 is a critical enzyme in the folate cycle, and it is involved in the metabolism of many different compounds, including nucleotides, amino acids, and metabolites. MTHFD2P7 is also involved in the regulation of cellular processes, including cell growth, apoptosis, and inflammation.

Given its involvement in the metabolism of many different compounds, MTHFD2P7 is a potential drug target or biomarker that can be targeted by small molecules. For example, MTHFD2P7 can be inhibited by small molecules such as nitrogen compounds, which can enhance the therapeutic effects of these compounds. Additionally, MTHFD2P7 can be activated by small molecules such as oxygen, which can enhance its catalytic activity.

In conclusion, MTHFD2P7 is a pseudogene that is involved in the metabolism of methenyltetrahydrofolate, a crucial coenzyme that is involved in many cellular processes. MTHFD2P7 is a potential drug target or biomarker due to its dependence on NADP+ and its involvement in the regulation of cellular processes. Further research is needed to fully understand the role of MTHFD2P7 in the folate cycle and its potential as a therapeutic target or biomarker.

Protein Name: Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2, Methenyltetrahydrofolate Cyclohydrolase Pseudogene 7

The "MTHFD2P7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MTHFD2P7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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