Target Name: NPPC
NCBI ID: G4880
Review Report on NPPC Target / Biomarker Content of Review Report on NPPC Target / Biomarker
NPPC
Other Name(s): CNP-53 | Natriuretic peptide C | C-type natriuretic peptide -53 | Type-C natriuretic peptide (CNP) | Nt-proCNP(1-74)_(HUMAN) | CNP-29 | CNP(51-103) | CNP-22 | ANFC_HUMAN | C-type natriuretic peptide N-terminal fragment (1-74) | N-terminal proCNP(1-74) | Nt-proCNP(1-81)_(HUMAN) | Nt-CNP(1-50) | Nt-proCNP(1-81) | C-type natriuretic peptide | natriuretic peptide C | N-terminal proCNP(1-81) | Nt-CNP(1-74) | natriuretic peptide precursor type C | CNP | Nt-proCNP(1-50) | CNP2 | Nt-proCNP(1-50)_(HUMAN) | C-type natriuretic peptide N-terminal fragment (1-50) | Nt-proCNP(1-74) | C-type natriuretic peptide N-terminal fragment (1-81) | Nt-CNP(1-81) | CNP-53_(HUMAN) | N-terminal proCNP(1-50)

Potential Drug Target and Biomarker for NPPC

NPPC (Nucleotide-Polymerase-Positive), also known as CNP-53, is a protein that is expressed in various cell types of the body, including the brain, heart, and kidneys. It is a key regulator of DNA replication and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and fertility disorders.

One of the most promising aspects of NPPC is its potential as a drug target. The ability of drugs to target specific proteins, such as NPPC, has led to the development of new treatments for a variety of diseases. By inhibiting the activity of NPPC, drugs can potentially interfere with the replication of DNA, leading to the growth inhibition and therapeutic effects associated with many diseases.

NPPC has also been identified as a potential biomarker for a number of diseases. The ability to detect and measure the level of NPPC in the body can potentially serve as a diagnostic tool for diseases that are characterized by disruptions in DNA replication. For example, the levels of NPPC have been shown to be elevated in the brains of individuals with Alzheimer's disease, a neurodegenerative disorder that is characterized by the progressive accumulation of neurofibrillary tangles and beta-amyloid plaques in the brain.

In addition to its potential as a drug target and biomarker, NPPC is also of interest to researchers as a potential therapeutic target for a number of diseases. The ability of drugs to target specific proteins, such as NPPC, has led to the development of new treatments for a variety of diseases. For example, drugs that inhibit the activity of NPPC have been shown to be effective in treating a variety of cancers, including breast, ovarian, and prostate cancers.

NPPC is also of interest to researchers as a potential target for neurodegenerative diseases. The progressive accumulation of neurofibrillary tangles and beta-amyloid plaques in the brain is a hallmark of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. The ability of drugs to target specific proteins, such as NPPC, has led to the development of new treatments for these disorders.

In addition to its potential as a therapeutic target, NPPC is also of interest to researchers as a potential biomarker for a number of diseases. The ability to detect and measure the level of NPPC in the body can potentially serve as a diagnostic tool for diseases that are characterized by disruptions in DNA replication. For example, the levels of NPPC have been shown to be elevated in the brains of individuals with Alzheimer's disease, a neurodegenerative disorder that is characterized by the progressive accumulation of neurofibrillary tangles and beta-amyloid plaques in the brain.

In conclusion, NPPC is a protein that is expressed in various cell types of the body and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and fertility disorders. Its potential as a drug target and biomarker is currently being investigated in a variety of settings. While more research is needed, the ability of drugs to target specific proteins, such as NPPC, has led to the development of new treatments for a variety of diseases and the potential for the development of new biomarkers for disease.

Protein Name: Natriuretic Peptide C

Functions: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation (By similarity). May also be vasoactive and natriuretic (PubMed:1672777). Acts by specifically binding and stimulating NPR2 to produce cGMP (PubMed:1672777, PubMed:21098034). Binds the clearance receptor NPR3 (PubMed:11533490)

The "NPPC Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NPPC comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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