Understanding The Role of NPY1R in Brain Processes (G4886)

Understanding The Role of NPY1R in Brain Processes

Neuropeptide Y receptor (NPY1R) is a G protein-coupled receptor that plays a crucial role in the regulation of various physiological processes in the brain. It is expressed in many different tissues and cells, including the hypothalamus, pituitary gland, and cardiovascular system, and is involved in the regulation of appetite, body weight, and stress responses.

NPY1R is a 15-amino acid protein that consists of an extracellular domain, a transmembrane region, and an intracellular domain. The extracellular domain is involved in the formation of the NPY1R complex, which consists of the extracellular domain, the transmembrane region, and the intracellular domain. The transmembrane region is responsible for the delivery of the neuropeptide Y1 (NPY1) molecule, which is the active ligand of the receptor.

The intracellular domain is responsible for the interaction between the NPY1R receptor and its ligand, the neuropeptide Y1. It includes a G protein-coupled receptor (GPCR) domain, which is responsible for the interaction with G protein-coupled receptors, as well as a catalytic domain, which is responsible for the catalytic activity of the receptor.

NPY1R is involved in the regulation of a wide range of physiological processes, including appetite, body weight, and stress responses. It is a key regulator of food intake and body weight, and is involved in the regulation of satiety and the control of body weight . It is also involved in the regulation of stress responses, including the regulation of anxiety and depression.

NPY1R is a potential drug target for the treatment of various psychiatric and neurological disorders, including obesity, anxiety and depression. Studies have shown that inhibition of NPY1R can lead to a reduction in appetite and an increase in body weight, which can be useful for the treatment of obesity. Additionally, inhibition of NPY1R has been shown to reduce the expression of genes involved in stress response, which can be useful for the treatment of anxiety and depression.

In addition to its potential therapeutic uses, NPY1R is also a potential biomarker for the diagnosis of various psychiatric and neurological disorders. The NPY1R gene has been shown to be involved in the regulation of various physiological processes, including appetite, body weight, and stress responses . Additionally, the expression of NPY1R has been shown to be involved in the development of certain psychiatric and neurological disorders, including obesity, anxiety and depression.

In conclusion, NPY1R is a G protein-coupled receptor that plays a crucial role in the regulation of various physiological processes in the brain. It is involved in the regulation of appetite, body weight, and stress responses, and is a potential drug target for the treatment of obesity and anxiety and depression. Additionally, it is also a potential biomarker for the diagnosis of these disorders. Further research is needed to fully understand the role of NPY1R in the regulation of physiological processes and its potential as a drug target.

Protein Name: Neuropeptide Y Receptor Y1

Functions: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid

The "NPY1R Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NPY1R comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

NPY2R | NPY4R | NPY4R2 | NPY5R | NPY6R | NQO1 | NQO2 | NR0B1 | NR0B2 | NR1D1 | NR1D2 | NR1H2 | NR1H3 | NR1H4 | NR1I2 | NR1I3 | NR2C1 | NR2C2 | NR2C2AP | NR2E1 | NR2E3 | NR2F1 | NR2F1-AS1 | NR2F2 | NR2F2-AS1 | NR2F6 | NR3C1 | NR3C2 | NR4A1 | NR4A2 | NR4A3 | NR5A1 | NR5A2 | NR6A1 | NRAD1 | NRADDP | NRAP | NRARP | NRAS | NRAV | NRBF2 | NRBF2P4 | NRBP1 | NRBP2 | NRCAM | NRDC | NRDE2 | NREP | NRF1 | NRG1 | NRG2 | NRG3 | NRG4 | NRGN | NRIP1 | NRIP2 | NRIP3 | NRIP3-DT | NRIR | NRK | NRL | NRM | NRN1 | NRN1L | NRON | NRP1 | NRP2 | NRROS | NRSN1 | NRSN2 | NRSN2-AS1 | NRTN | NRXN1 | NRXN2 | NRXN2-AS1 | NRXN3 | NSA2 | NSA2P2 | NSD1 | NSD2 | NSD3 | NSDHL | NSF | NSFL1C | NSFP1 | NSG1 | NSG2 | NSL complex | NSL1 | NSMAF | NSMCE1 | NSMCE1-DT | NSMCE2 | NSMCE3 | NSMCE4A | NSMF | NSRP1 | NSUN2 | NSUN3 | NSUN4