Target Name: POLK
NCBI ID: G51426
Review Report on POLK Target / Biomarker Content of Review Report on POLK Target / Biomarker
POLK
Other Name(s): DINB protein | POLQ | POLK variant 1 | DNA polymerase kappa | DINB1 | polymerase (DNA directed) kappa | POLK_HUMAN | DINP | DNA polymerase kappa (isoform 1) | DNA-directed DNA polymerase kappa

Polk (DINB) Protein: A Promising Drug Target and Biomarker

Polk (DINB) protein is a unique and highly conserved protein that plays a critical role in various cellular processes. It is a non-coding RNA molecule that belongs to the HURF/PYRNA family. Polk protein is expressed in most tissues and cells of the human body and is involved in various cellular processes, including DNA replication, gene expression, and cell signaling.

Polk protein has been identified as a potential drug target and biomarker due to its unique structure, stability, and involvement in disease. In this article, we will discuss the biology of Polk protein, its potential drug targeting, and its role as a biomarker for various diseases.

Biography of Polk Protein

Polk protein is a 193-amino acid protein that contains a unique open-ended structure. It has a characteristic 尾-sheet and a 尾-hairpin that give it a unique 3D structure. The 尾-sheet is the most conserved region of the protein and is involved in the stability and structure of the protein. The 尾-hairpin is a unique region that is involved in the regulation of protein stability and interactions.

Polk protein is expressed in most tissues and cells of the human body, including the brain, heart, muscle, and gastrointestinal tract. It is involved in various cellular processes, including DNA replication, gene expression, and cell signaling.

Polk protein has been shown to play a critical role in the regulation of cell proliferation and apoptosis. It has been shown to promote the growth of cancer cells and contribute to their survival. In addition, Polk protein has been shown to play a critical role in the regulation of stem cell proliferation and differentiation.

Polk protein has also been shown to be involved in the regulation of inflammation and immune responses. It has been shown to contribute to the regulation of immune cell function and the regulation of inflammation.

Polk protein is a potential drug target due to its unique structure and involvement in various cellular processes that are associated with disease.

Potential Drug Target

Polk protein has been shown to be involved in various cellular processes that are associated with disease, including cancer, inflammation, and neurodegenerative diseases. As a potential drug target, Polk protein is being investigated for its potential therapeutic applications.

One of the potential therapeutic applications of Polk protein is its potential to treat cancer. Polk protein has been shown to promote the growth of cancer cells and contribute to their survival. Therefore, Polk protein may be a useful target for cancer therapies that target its activity.

Another potential therapeutic application of Polk protein is its potential to treat neurodegenerative diseases. Polk protein has been shown to play a critical role in the regulation of stem cell proliferation and differentiation, which may be involved in the development of neurodegenerative diseases. Therefore, Polk protein may be a useful target for neurodegenerative disease therapies.

In addition to its potential therapeutic applications, Polk protein is also being investigated as a potential biomarker for various diseases.

Potential Biomarker

Polk protein has been shown to be involved in various cellular processes that are associated with disease, including cancer, inflammation, and neurodegenerative diseases. Therefore, Polk protein may be a useful biomarker for these diseases.

One of the potential applications of Polk protein as a biomarker is its ability to be used as a diagnostic marker for cancer. Polk protein has been shown to be expressed in various types of cancer cells and has been shown to play a critical role in the regulation of cancer cell growth and survival. Therefore, Polk protein may be a useful

Protein Name: DNA Polymerase Kappa

Functions: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity

The "POLK Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about POLK comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

POLL | POLM | POLN | POLQ | POLR1A | POLR1B | POLR1C | POLR1D | POLR1E | POLR1F | POLR1G | POLR1H | POLR1HASP | POLR2A | POLR2B | POLR2C | POLR2D | POLR2E | POLR2F | POLR2G | POLR2H | POLR2I | POLR2J | POLR2J2 | POLR2J3 | POLR2J4 | POLR2K | POLR2L | POLR2LP1 | POLR2M | POLR3A | POLR3B | POLR3C | POLR3D | POLR3E | POLR3F | POLR3G | POLR3GL | POLR3H | POLR3K | POLRMT | POLRMTP1 | Poly [ADP-ribose] polymerase | Polycomb Repressive Complex 1 (PRC1) | Polycomb Repressive Complex 2 | POM121 | POM121B | POM121C | POM121L12 | POM121L15P | POM121L1P | POM121L2 | POM121L4P | POM121L7P | POM121L8P | POM121L9P | POMC | POMGNT1 | POMGNT2 | POMK | POMP | POMT1 | POMT2 | POMZP3 | PON1 | PON2 | PON3 | POP1 | POP4 | POP5 | POP7 | POPDC2 | POPDC3 | POR | PORCN | POSTN | POT1 | POT1-AS1 | Potassium Channels | POTEA | POTEB | POTEB2 | POTEB3 | POTEC | POTED | POTEE | POTEF | POTEG | POTEH | POTEI | POTEJ | POTEKP | POTEM | POU-Domain transcription factors | POU1F1 | POU2AF1 | POU2AF2 | POU2AF3 | POU2F1 | POU2F2