Target Name: POLR1G
NCBI ID: G10849
Review Report on POLR1G Target / Biomarker Content of Review Report on POLR1G Target / Biomarker
POLR1G
Other Name(s): RPA34 | RNA polymerase I subunit G | DNA-directed RNA polymerase I subunit RPA34 | CD3e molecule, epsilon associated protein | POLR1G variant 2 | CD3e antigen, epsilon polypeptide associated protein | RNA polymerase I subunit G, transcript variant 2 | RNA polymerase I-associated factor PAF49 | MGC118851 | CD3EAP | Antisense to ERCC-1 protein | CD3E antigen, epsilon polypeptide associated protein | CD3e molecule associated protein | A34.5 | PAF49 | ASE-1 | CD3 epsilon associated protein | CD3-epsilon-associated protein | CAST | DNA-directed RNA polymerase I subunit G | ASE1 | RPA34_HUMAN | Anti-sense to ERCC-1 protein | Antisense to ERCC 1 | CD3E-associated protein | antisense to ERCC-1 protein | DNA-directed RNA polymerase I subunit RPA34 (isoform 2)

POLR1G: Potential Drug Target for Neurological Disorders

POLR1G (PRT1G) is a protein that is expressed in the brain and is known for its role in the regulation of microRNA (miRNA) levels. It has been shown to play a crucial role in the development and progression of several neurological disorders, including Alzheimer's disease and Parkinson's disease.

Recent studies have also suggested that POLR1G may have potential as a drug target or biomarker for certain neurological disorders. For example, some researchers have found that targeting the expression of POLR1G has been shown to improve cognitive function in individuals with Alzheimer's disease.

Additionally, other studies have shown that targeting the miRNA levels of POLR1G has been shown to be effective in reducing the amount of neurodegeneration in individuals with Parkinson's disease.

The potential drug targets for POLR1G are still being explored, but it is clear that it is an important protein that is involved in the development and progression of several neurological disorders. Further research is needed to fully understand its role and potential as a drug target or biomarker.

Protein Name: RNA Polymerase I Subunit G

Functions: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation

The "POLR1G Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about POLR1G comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

POLR1H | POLR1HASP | POLR2A | POLR2B | POLR2C | POLR2D | POLR2E | POLR2F | POLR2G | POLR2H | POLR2I | POLR2J | POLR2J2 | POLR2J3 | POLR2J4 | POLR2K | POLR2L | POLR2LP1 | POLR2M | POLR3A | POLR3B | POLR3C | POLR3D | POLR3E | POLR3F | POLR3G | POLR3GL | POLR3H | POLR3K | POLRMT | POLRMTP1 | Poly [ADP-ribose] polymerase | Polycomb Repressive Complex 1 (PRC1) | Polycomb Repressive Complex 2 | POM121 | POM121B | POM121C | POM121L12 | POM121L15P | POM121L1P | POM121L2 | POM121L4P | POM121L7P | POM121L8P | POM121L9P | POMC | POMGNT1 | POMGNT2 | POMK | POMP | POMT1 | POMT2 | POMZP3 | PON1 | PON2 | PON3 | POP1 | POP4 | POP5 | POP7 | POPDC2 | POPDC3 | POR | PORCN | POSTN | POT1 | POT1-AS1 | Potassium Channels | POTEA | POTEB | POTEB2 | POTEB3 | POTEC | POTED | POTEE | POTEF | POTEG | POTEH | POTEI | POTEJ | POTEKP | POTEM | POU-Domain transcription factors | POU1F1 | POU2AF1 | POU2AF2 | POU2AF3 | POU2F1 | POU2F2 | POU2F3 | POU3F1 | POU3F2 | POU3F3 | POU3F4 | POU4F1 | POU4F2 | POU4F3 | POU5F1 | POU5F1B | POU5F1P3