Identifying Potential Drug Targets or Biomarkers for PDE11A (G105373764)

Target Name: PDE11A-AS1

NCBI ID: G105373764

PDE11A-AS1

Other Name(s): PDE11A antisense RNA 1

Identifying Potential Drug Targets or Biomarkers for PDE11A

Protein-DNA interactions are crucial for many cellular processes, including DNA replication, gene expression, and cell signaling. One of the key regulators of these interactions is the protein PDE11A, which is a member of the PDE11 family of enzymes. PDE11A is widely expressed in various tissues and has been implicated in a number of cellular processes, including cell signaling, cell division, and tissue repair.

In recent years, researchers have been interested in identifying potential drug targets or biomarkers for PDE11A. One of the most promising candidates is PDE11A-AS1, a translation of the PDE11A gene that is linked to the development of a number of diseases, including cancer. In this article, we will explore the biology of PDE11A and PDE11A-AS1, and discuss their potential as drug targets or biomarkers.

PDE11A: A Complex Enzyme

PDE11A is a member of the PDE11 family of enzymes, which are known for their ability to catalyze the hydrolysis of DNA-protein bonds. These enzymes have been identified in a variety of organisms, including bacteria, yeast, and animals, and are involved in a wide range of cellular processes, including DNA replication, gene expression, and cell signaling.

PDE11A is a 21-kDa protein that is expressed in various tissues, including muscle, heart, liver, and brain. It is highly conserved, with a calculated amino acid sequence of 21.1% identity to mouse PDE11A and 19.9% identity to human PDE11A. PDE11A is localized to the endoplasmic reticulum (ER) and has been shown to play a role in regulating the levels of various proteins in the cell.

Function and Interactions

PDE11A is involved in a wide range of cellular processes, including the regulation of DNA replication, gene expression, and cell signaling. One of its most well-studied functions is its role in regulating the levels of the protein p53, which is a key regulator of DNA damage repair.

PDE11A has been shown to play a positive role in the regulation of p53. Studies have shown that PDE11A can interact with p53 and promote its stability in the ER. This interaction between PDE11A and p53 is important for the regulation of p53 function, as it allows p53 to function as a critical regulator of DNA damage repair.

In addition to its role in regulating p53, PDE11A is also involved in the regulation of other proteins. For example, it has been shown to play a role in the regulation of the protein TATA-associated RNA polymerase (TASP), which is involved in the regulation of gene expression.

PDE11A-AS1: A Potential Drug Target

PDE11A-AS1 is a translation of the PDE11A gene that has been linked to the development of a number of diseases, including cancer. It is a 21.2-kDa protein that is highly conserved and has a calculated amino acid sequence of 21.1% identity to mouse PDE11A and 19.9% identity to human PDE11A.

PDE11A-AS1 has been shown to play a role in the regulation of cellular processes, including cell signaling and cell division. For example, studies have shown that PDE11A-AS1 can interact with the protein SIRT1, which is involved in the regulation of cellular processes such as DNA replication and repair.

In addition to its role in regulating cellular processes, PDE11A-AS1 is also shown to play a role in the regulation of

Protein Name: PDE11A Antisense RNA 1

The "PDE11A-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PDE11A-AS1 comprehensively, including but not limited to:
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•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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