PDE10A: A Protein Involved in Cell Regulation and Disease (G10846)

Target Name: PDE10A

NCBI ID: G10846

PDE10A

PDE10A: A Protein Involved in Cell Regulation and Disease

PDE10A (ADSD2), a member of the adenylyl cyclase subfamily, is a protein that is expressed in various tissues throughout the body. It plays a crucial role in the regulation of cellular processes that are essential for proper physiological function. One of the most significant functions of PDE10A is its role in the regulation of ion channels, which are responsible for the flow of electrical currents through cells.

PDE10A is a transmembrane protein, which means that it spans the membrane of the cell and is involved in the regulation of the movement of ions and other molecules across the membrane. This is accomplished through its ability to interact with various molecules, including other proteins and ion channels.

One of the most significant functions of PDE10A is its role in the regulation of ion channels. Many ions, including calcium and potassium ions, are involved in the regulation of various cellular processes, including muscle contractions, nerve signals, and even the contraction and relaxation of blood vessels. PDE10A plays a critical role in the regulation of these ion channels, as it is able to interact with these channels and regulate the flow of ions through them.

In addition to its role in ion channel regulation, PDE10A is also involved in the regulation of various cellular processes that are essential for proper physiological function. For example, PDE10A is involved in the regulation of cell growth, as it has been shown to play a role in the regulation of cell proliferation.

PDE10A is also involved in the regulation of cellular death, as it has been shown to play a role in the regulation of apoptosis, which is the process by which cells die when they are no longer needed. This is accomplished through its ability to interact with various molecules, including the protein Bcl-2, which is known to play a critical role in the regulation of apoptosis.

In conclusion, PDE10A (ADSD2) is a protein that is involved in the regulation of various cellular processes that are essential for proper physiological function. Its role in the regulation of ion channels, cell growth, and apoptosis makes it an attractive drug target and a potential biomarker for various diseases. Further research is needed to fully understand the role of PDE10A in cellular processes and its potential as a drug target.

Protein Name: Phosphodiesterase 10A

Functions: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides (PubMed:10373451, PubMed:10393245, PubMed:16330539, PubMed:27058447, PubMed:17389385). Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate (PubMed:10373451, PubMed:10393245, PubMed:27058447, PubMed:17389385). May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition (PubMed:27058447)

The "PDE10A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PDE10A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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